Togni’s Reagent CAS 887144-97-0
Identification
CAS Number
887144-97-0
Name
3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Synonyms
1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Togni’s Reagent
Trifluoromethyl-1,3-dihydro-3,3-dimethyl-1,2-benziodoxole
1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole
Molecular Structure
SMILES
CC1(c2ccccc2I(O1)C(F)(F)F)C
StdInChI
InChI=1S/C10H10F3IO/c1-9(2)7-5-3-4-6-8(7)14(15-9)10(11,12)13/h3-6H,1-2H3
StdInChIKey
HVAPLSNCVYXFDQ-UHFFFAOYSA-N
MDL Number
MFCD10567056
Molecular Formula
C10H10F3IO
Molecular Weight
330.08
Properties
Appearance
White crystal
Melting Point
75-79 °C
Safety Data
Symbol
GHS07
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
26-36/37
WGK Germany
3
Specifications and Other Information of Our Togni’s Reagent CAS 887144-97-0
Identification Methods
HNMR, FNMR, HPLC
Assay
98% min
Productivity
20kg/month
Application
• Selective trifluoromethylation of 1,3-disubstituted arenes through iridium-catalyzed arene borylation and copper-catalyzed trifluoromethylation1
• Copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with electrophilic trifluoromethylating reagent2
• Pd-catalyzed electrophilic ortho-trifluoromethylation of arenes using trifluoroacetic acid as a promotor3
Used in the Preparation of
• Trifluoromethylimidoylethyl substituted heterocycles via bis(trifluoromethylsulfonyl)amine-catalyzed Rotter type reaction of heterocycles with nitriles in presence of trifluoromethylbenziodoxole4
• Stereoselective synthesis of α-trifluoromethyl aldehydes via trimethylbenzylimidazolidinone and copper-catalyzed enantioselective α-trifluoromethylation of aldehydes with iodonium salts5
General View of Doccuments
Togni-s Reagent CAS 887144-97-0 HNMR
Togni-s Reagent CAS 887144-97-0 FNMR
Links
Watson International Ltd
This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://watson-int.com/tognis-reagent-cas-887144-97-0/
