Togni’s Reagent CAS 887144-97-0

Identification

CAS Number

887144-97-0

Name

3,3-Dimethyl-1-(trifluoromethyl)-1,2-benziodoxole

Synonyms

1,3-Dihydro-3,3-dimethyl-1-(trifluoromethyl)-1,2-benziodoxole
Togni’s Reagent
Trifluoromethyl-1,3-dihydro-3,3-dimethyl-1,2-benziodoxole
1-Trifluoromethyl-3,3-dimethyl-1,2-benziodoxole

Molecular Structure

SMILES

CC1(c2ccccc2I(O1)C(F)(F)F)C

StdInChI

InChI=1S/C10H10F3IO/c1-9(2)7-5-3-4-6-8(7)14(15-9)10(11,12)13/h3-6H,1-2H3

StdInChIKey

HVAPLSNCVYXFDQ-UHFFFAOYSA-N

MDL Number

MFCD10567056

Molecular Formula

C10H10F3IO

Molecular Weight

330.08

Properties

Appearance

White crystal

Melting Point

75-79 °C

Safety Data

Symbol

GHS07

Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Hazard Codes (Europe)

Xi

Risk Statements (Europe)

36/37/38

Safety Statements (Europe)

26-36/37

WGK Germany

3

Specifications and Other Information of Our Togni’s Reagent CAS 887144-97-0

Identification Methods

HNMR, FNMR, HPLC

Assay

98% min

Productivity

20kg/month

Application

• Selective trifluoromethylation of 1,3-disubstituted arenes through iridium-catalyzed arene borylation and copper-catalyzed trifluoromethylation1
• Copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with electrophilic trifluoromethylating reagent2
• Pd-catalyzed electrophilic ortho-trifluoromethylation of arenes using trifluoroacetic acid as a promotor3

Used in the Preparation of
• Trifluoromethylimidoylethyl substituted heterocycles via bis(trifluoromethylsulfonyl)amine-catalyzed Rotter type reaction of heterocycles with nitriles in presence of trifluoromethylbenziodoxole4
• Stereoselective synthesis of α-trifluoromethyl aldehydes via trimethylbenzylimidazolidinone and copper-catalyzed enantioselective α-trifluoromethylation of aldehydes with iodonium salts5

General View of Doccuments

Togni-s Reagent CAS 887144-97-0 HNMR

Togni-s Reagent CAS 887144-97-0 FNMR

Links

Watson International Ltd

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://watson-int.com/tognis-reagent-cas-887144-97-0/