Togni Reagent II CAS 887144-94-7
Identification
CAS Number
887144-94-7
Name
Togni Reagent II
Synonyms
1-(Trifluoromethyl)-1,2-benziodoxol-3(1H)-one
1,2-Benziodoxol-3(1H)-one, 1-(trifluoromethyl)-
1-Trifluoromethyl-1,2-benziodoxol-3-(1H)-one
Molecular Structure
SMILES
c1ccc2c(c1)C(=O)OI2C(F)(F)F
StdInChI
InChI=1S/C8H4F3IO2/c9-8(10,11)12-6-4-2-1-3-5(6)7(13)14-12/h1-4H
StdInChIKey
XHEOXSQMBWJOKP-UHFFFAOYSA-N
Molecular Formula
C8H4F3IO2
Molecular Weight
316.02
Properties
Appearance
White crystal
Melting Point
122 °C
Safety Data
Symbol
GHS07,GHS08
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
26-36/37
WGK Germany
3
Special Notiee
This intermediate is high-energy compound and may explode under heat, friction or striking. A similiar compound Togni’s Reagent CAS 887144-97-0 is recommended for safer transportation and storage.
Specifications and Other Information of Our Togni Reagent II CAS 887144-94-7
Identification Methods
HNMR, FNMR, HPLC
Assay
98% min
Productivity
20kg/month
Application
• Selective trifluoromethylation of 1,3-disubstituted arenes through iridium-catalyzed arene borylation and copper-catalyzed trifluoromethylation1
• Copper-catalyzed trifluoromethylation of aryl- and alkenylboronic acids with electrophilic trifluoromethylating reagent2
• Pd-catalyzed electrophilic ortho-trifluoromethylation of arenes using trifluoroacetic acid as a promotor3
Used in the Preparation of
• Trifluoromethylimidoylethyl substituted heterocycles via bis(trifluoromethylsulfonyl)amine-catalyzed Rotter type reaction of heterocycles with nitriles in presence of trifluoromethylbenziodoxole4
• Stereoselective synthesis of α-trifluoromethyl aldehydes via trimethylbenzylimidazolidinone and copper-catalyzed enantioselective α-trifluoromethylation of aldehydes with iodonium salts5
General View of Doccuments
Links
Watson International Ltd
This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://watson-int.com/togni-reagent-ii-cas-887144-94-7/
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