Structure of Ticagrelor CAS 274693-27-5

Ticagrelor CAS 274693-27-5

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Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

274693-27-5

Name

Ticagrelor

Synonyms

(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol [ACD/IUPAC Name]
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorophényl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyéthoxy)-1,2-cyclopentanediol [French] [ACD/IUPAC Name]
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-{[(1R,2S)-2-(3,4-Difluorphenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentandiol [German] [ACD/IUPAC Name]
1,2-cyclopentanediol, 3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-, (1S,2S,3R,5S)- [ACD/Index Name]
274693-27-5 [RN]
8772
Brilinta [Trade name]
Brilique [Trade name]
GLH0314RVC
Possia [Trade name]
Ticagrelor [Wiki]
(1S,?2S,?3R,?5S)?-3-?[7-?[[(1R,?2S)?-?2-?(3,?4-?difluorophenyl)?cyclopropyl]?amino]?-?5-?(propyl-?1,?1,?2,?2,?3,?3,?3-?d7-?thio)?-?3H-?1,?2,?3-?triazolo[4,?5-?d]?pyrimidin-?3-?yl]?-?5-?(2-?hydroxyethoxy)?-1,?2-?Cyclopentanediol?
(1S,2S,3R,5S)-3-(7-(((1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl)amino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-Difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-(1,2,3)triazolo(4,5-d)pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-(7-((1R,2S)-2-(3,4-difluorophenyl)cyclopropylamino)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-(7-{[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino}-5-(propylsulfanyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-3-yl)-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3-triazolo[4,5-d]pyrimidinyl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3-triazolo[5,4-d]pyrimidinyl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-(propylthio)triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyl-[1,2,3]triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyltriazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-difluorophenyl)cyclopropyl]amino]-5-propylsulfanyl-triazolo[5,4-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)cyclopentane-1,2-diol
;(1S,2S,3R,5S)-3-[7-[[(1R,2S)-2-(3,4-Difluorophenyl)cyclopropyl]amino]-5-(propylthio)-3H-1,2,3-triazolo[4,5-d]pyrimidin-3-yl]-5-(2-hydroxyethoxy)-1,2-cyclopentanediol
[14C]-Ticagrelor
[274693-27-5]
1265911-55-4 [RN]
AR-C 126532XX
AR-C 126532XX; AZD 6140;AZD6140;AZD-6140
AR-C126532XX|AZD6140|Brilinta®|Brilique®
Brilinta®
Brilique (Trade name)
Brilique®
Brilique; Possia
compound 17 [PMID: 17827008]
MFCD09954148 [MDL number]
Ticagrelor(AZD6140)
TIQ
UNII:GLH0314RVC
UNII-GLH0314RVC

Molecular Structure

Structure of Ticagrelor CAS 274693-27-5

Structure of Ticagrelor CAS 274693-27-5

SMILES

CCCSc1nc(c2c(n1)n(nn2)[C@@H]3C[C@@H]([C@H]([C@H]3O)O)OCCO)N[C@@H]4C[C@H]4c5ccc(c(c5)F)F

StdInChI

InChI=1S/C23H28F2N6O4S/c1-2-7-36-23-27-21(26-15-9-12(15)11-3-4-13(24)14(25)8-11)18-22(28-23)31(30-29-18)16-10-17(35-6-5-32)20(34)19(16)33/h3-4,8,12,15-17,19-20,32-34H,2,5-7,9-10H2,1H3,(H,26,27,28)/t12-,15+,16+,17-,19-,20+/m0/s1

StdInChIKey

OEKWJQXRCDYSHL-FNOIDJSQSA-N

Molecular Formula

C23H28F2N6O4S

Molecular Weight

522.57

Properties

Appearance

White to pale pink crystalline powder

Safety Data

WGK Germany

3

MSDS

Ticagrelor CAS 274693-27-5 MSDS

Specifications and Other Information of Our Ticagrelor CAS 274693-27-5

Standard

Enterprise standard

Identification Methods

HPLC

Purity

99%min

Specific Optical Rotation

-50°~ -56°

Heavy Metals

≤10pppm

Chloride

≤0.01%

Loss on Drying

≤0.5%

Residue on Ignition

≤0.1%

Residual Solvents

Ethylacetate

≤5000pppm

Petroleum ether(calculate by n-hexane)

≤290pppm

Related Substance

Impurity A

≤0.1%

Impurity B

≤0.1%

Impurity C

≤0.1%

Impurity D

≤0.1%

Any Unknow Impurity

≤0.1%

Total Impurities

≤1.0%

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light

Application

It is an anticoagulant; often used to reduce cardiovascular death and heart attack in patients with acute coronary syndrome (ACS).

Links

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/ticagrelor-cas-274693-27-5/

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/ticagrelor-cas-274693-27-5/

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