Tetrabromophenol Blue CAS 4430-25-5

Identification

CAS Number

4430-25-5

Name

Tetrabromophenol Blue

Synonyms

4,4′-(4,5,6,7-tetrabrom-1,1-dioxido-3h-2,1-benzoxathiol-3,3-diyl)bis(2,6-dibrombenzolol)
4,4′-(4,5,6,7-Tetrabrom-1,1-dioxido-3H-2,1-benzoxathiol-3,3-diyl)bis(2,6-dibromphenol)
4,4′-(4,5,6,7-Tetrabromo-1,1-dioxido-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromophenol)
4,4′-(4,5,6,7-Tétrabromo-1,1-dioxydo-3H-2,1-benzoxathiole-3,3-diyl)bis(2,6-dibromophénol)
Phenol, 4,4′-(4,5,6,7-tetrabromo-1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromo-
4,4′-(4,5,6,7-tetrabromo-3h-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromophenol) s,s-dioxide
3,3′,3”,4,5,5′,5”,6-Octabromophenolsulfonphthalein
3′,3”,5′,5”-Tetrabromophenol-4,5,6,7-tetrabromosulfonephthalein
3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4,5,6,7-tetrabromobenzo[c]1,2-oxathiolene -1,1-dione
3,3-bis(3,5-dibromo-4-hydroxyphenyl)-4,5,6,7-tetrabromobenzo[c]1,2-oxathiolene-1,1-dione
3,4,5,6,3′,5′,3”,5”-Octabromophenolsulfonphthalein
4,4′-(4,5,6,7-Tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis(2,6-dibromophenol) S,S-dioxide
4,4′-(4,5,6,7-tetrabromo-3H-2,1-benzoxathiol-3-ylidene)bis[2,6-dibromophenol] S,S-dioxide
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-2,1λ6-benzoxathiole-1,1(3H)-dione
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxyphenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
4,5,6,7-Tetrabromo-3,3-bis(3,5-dibromo-4-hydroxy-phenyl)-3H-benzo[c][1,2]oxathiole 1,1-dioxide
Benzenesulfonic acid, 2-(bis(3,5-dibromo-4-hydroxyphenyl)hydroxymethyl)-3,4,5,6-tetrabromo- (9CI)
Tetrabromophenol blue
Tetrabromophenyl blue
Tetrabromphenol tetrabromsulfonphthalein

Molecular Structure

SMILES

C1=C(C=C(C(=C1Br)O)Br)C2(C3=C(C(=C(C(=C3Br)Br)Br)Br)S(=O)(=O)O2)C4=CC(=C(C(=C4)Br)O)Br

StdInChI

InChI=1S/C19H6Br8O5S/c20-7-1-5(2-8(21)16(7)28)19(6-3-9(22)17(29)10(23)4-6)11-12(24)13(25)14(26)15(27)18(11)33(30,31)32-19/h1-4,28-29H

StdInChIKey

QPMIVFWZGPTDPN-UHFFFAOYSA-N

Molecular Formula

C19H6Br8O5S

Molecular Weight

985.54

EINECS

224-622-9

MDL Number

MFCD00005876

Beilstein Registry Number

378438

Properties

Appearance

Yellow or brown powder

Melting Point

203-205 ºC

Safety Data

Personal Protective Equipment

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

WGK Germany

3

Specifications and Other Information of Our Tetrabromophenol Blue CAS 4430-25-5

Identification Methods

HNMR,HPLC

Purity

97% min

Loss on Drying

1.0% max

Water

1.0% max

Ash

1.0% max

Bromide

5.0% max

Iodide

0.1% max

Pb

20ppm max

Hg

1ppm max

AS

3ppm max

Fe

100ppm max

Solvent Residue

0.1ppm max

Storage

Store in a cool(2-8 °C) and dry place, and away from light

Application

Applications of analytical chemistry and biotechnology
pH Indicator
Color change range: around pH 3.0 – 4.6
Color shift:
Acidic: Yellow
Alkaline: Blue
Application: Often used in titrations and buffer systems for acidic pH detection.
Protein Detection (Electrophoresis and Staining)
Acts as a tracking dye during SDS-PAGE or agarose gel electrophoresis to monitor the progress of protein migration.
Used as a staining agent for proteins on membranes (e.g., nitrocellulose or PVDF) in colorimetric detection.
Analytical Reagent
Forms complexes with certain compounds (e.g., proteins or surfactants), making it useful in quantitative assays.
Can be used in spectrophotometric methods to measure concentrations of biomolecules or ions.
Biochemical and Diagnostic Kits
May be included in enzyme-linked assays, diagnostic strips, or colorimetric test kits where pH changes or protein levels are indicators.

Application of hair dye
pH-responsive color-changing hair dye (color shift effect)
Since it is a pH indicator, its color changes from yellow to blue depending on the pH level, making it suitable for:
Temporary hair dyes: forming a color layer on the hair surface.
Toy or children’s color-changing hair products: using low-irritation acidic or alkaline systems to create visual effects.
“Color-changing hair” products: for example, changing color during washing, or in response to water, heat, or UV light.
Binding to proteins to color hair
Human hair is primarily composed of keratin, a type of protein.
Tetrabromophenol Blue is commonly used in laboratory experiments to detect proteins, and under certain conditions, it may bind to hair proteins to produce a coloring effect.

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Links

This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).

This product is sold exclusively through our sales company Watson International Limited, and please click the link below for details (https://www.watson-int.com/).