Terbinafine Hydrochloride CAS 78628-80-5

Identification

CAS Number

78628-80-5

Name

Terbinafine Hydrochloride

Synonyms

(2E)-N,6,6-Trimethyl-N-(1-naphthylmethyl)-2-hepten-4-in-1-aminhydrochlorid (1:1) [German] [ACD/IUPAC Name]
(2E)-N,6,6-Trimethyl-N-(1-naphthylmethyl)-2-hepten-4-yn-1-amine hydrochloride (1:1) [ACD/IUPAC Name]
(2E)-N,6,6-Trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine hydrochloride (1:1)
(2E)-N,6,6-Triméthyl-N-(1-naphtylméthyl)-2-heptén-4-yn-1-amine, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
(2E)-N,6,6-triméthyl-N-(naphtalén-1-ylméthyl)hept-2-én-4-yn-1-amine chlorhydrate [French]
(2E)-N,6,6-Trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-in-1-aminhydrochlorid
(2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
(2E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride (1:1)
1-Naphthalenemethanamine, N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-, hydrochloride (1:1) [ACD/Index Name]
78628-80-5 [RN]
Lamisil [Trade name]
MFCD00145430 [MDL number]
QJ8600100
Terbinafine HCl
Terbinafine hydrochloride
trans-N-(6,6-Dimethyl-2-hepten-4-ylyl)-N-methyl-1-naphthylmethylamine hydrochloride
trans-N-Methyl-N-(1-naphthylmethyl)-6,6-dimethylhept-2-en-4-ynyl-1-amine hydrochloride
({(2E)-6,6-Dimethylhept-2-en-4-yn-1-ylamino}methyl)naphthalene hydrochloride
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine hydrochloride
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine hydrochloride
(E)-N,6,6-trimethyl-N-(1-naphthalenylmethyl)-1-hept-2-en-4-ynamine hydrochloride
(E)-N,6,6-trimethyl-N-(1-naphthylmethyl)hept-2-en-4-yn-1-amine hydrochloride
(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine hydrochloride
1185240-27-0 [RN]
1-Naphthalenemethanamine, N-(6,6-dimethyl-2-hepten-4-ynyl)-N-methyl-, (E)-, monohydrochloride
202-829-5 [EINECS]
616-640-4 [EINECS]
Afogan
Bramazil
cis-Terbinafine Hydrochloride
Corbinal
HYDROGEN TERBINAFINE CHLORIDE
hydron;(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;chloride
InnoNyx
LAMISIL AT
LAMISIL HYDROCHLORIDE
Lamisil Krem
MFCD00000693 [MDL number]
mycoCeaze
MycoVa
N-[(2E)-6,6-dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine, monohydrochloride
QA-2611
Sebifin
SF 86-327 hydrochloride
TerbiFoam
Terbinafine hydrochioride
terbinafine monohydrochloride
Terbisil
trans-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthylmethylamine Hydrochloride
WZ1797000
Zabel
Zimig

Molecular Structure

Structure of Terbinafine Hydrochloride CAS 78628-80-5
Structure of Terbinafine Hydrochloride CAS 78628-80-5

SMILES

CC(C)(C)C#C/C=C/CN(C)Cc1cccc2c1cccc2.Cl

StdInChI

InChI=1S/C21H25N.ClH/c1-21(2,3)15-8-5-9-16-22(4)17-19-13-10-12-18-11-6-7-14-20(18)19;/h5-7,9-14H,16-17H2,1-4H3;1H/b9-5+;

StdInChIKey

BWMISRWJRUSYEXSZKNIZGXSA-N

Molecular Formula

C21H25N · HCl 

Molecular Weight

327.89

MDL Number

MFCD00145430

Properties

Appearance

White or almost white powder

Safety Data

Symbol

exclamation-mark-jpgexclamation-mark-jpgGHS07, GHS09

Signal Word

Warning

Hazard statements

H315-H319-H335-H410

Precautionary Statements

P261-P273-P305 + P351 + P338-P501

Supplemental Hazard Statements 

Risk of explosion if heated under confinement.

Personal Protective Equipment

dust mask type N95 (US)EyeshieldsGloves

RIDADR 

UN 3077 9 / PGIII

WGK Germany

3

RTECS 

QJ8600100

Specifications and Other Information of Our Terbinafine Hydrochloride CAS 78628-80-5

Identification Methods

IR

Assay

99.0%-101.0%

Particle Size

90% NMT 50μm

Related Substances

Impurity B

≤0.15%

Impurity E

≤0.05%

Unspecified impurities

Each Impurity ≤0.1%

Loss on Drying

≤0.5%

Sulfated ash

≤0.1%

Residual Solvent

Ethyl acetate

≤0.5%

Dichloromethane

≤0.06%

Isopropanol

≤0.5%

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Terbinafine Hydrochloride is a kind of acrylamine drug with broad-spectrum antifungal activity. It has significant curative effect on athlete’s foot, onychomycosis, body lice, femur and tinea versicolor caused by fungi. It can also be used in bronchial tubes. Asthma, asthmatic bronchitis and emphysema.

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details. http://www.caming.com/terbinafine-hydrochloride-cas-78628-80-5/ This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/terbinafine-hydrochloride-cas-78628-80-5/
Posted in APIs, Caming Pharmaceutical Ltd, Products