Structure of Tenofovir alafenamide CAS 379270-37-8

Tenofovir alafenamide CAS 379270-37-8

Identification

CAS Number

379270-37-8

Name

Tenofovir alafenamide

Synonyms

379270-37-8 [RN]
383365-04-6 [RN]
Isopropyl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate [ACD/IUPAC Name]
Isopropyl-N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)-2-propanyl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninat [German] [ACD/IUPAC Name]
J4414G3BUK
L-Alanine, N-[(S)-[(1S)-[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethoxy]methyl]phenoxyphosphinyl]-, 1-methylethyl ester [ACD/Index Name]
N-[(S)-({[(2R)-1-(6-Amino-9H-purin-9-yl)-2-propanyl]oxy}méthyl)(phénoxy)phosphoryl]-L-alaninate d’isopropyle [French] [ACD/IUPAC Name]
tenofovir alafenamida [Spanish] [INN]
Tenofovir alafenamide [USAN]
ténofovir alafénamide [French] [INN]
tenofovirum alafenamidum [Latin] [INN]
тенофовир алафенамид [Russian] [INN]
تينوفوفير ألافيناميد [Arabic] [INN]
磷丙替诺福韦 [Chinese] [INN]
(S)-Isopropyl 2-(((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)amino)propanoate
[379270-37-8]
79270-37-8
bis{9-[(2R,5S,7E)-2,7,10-trimethyl-5,8-dioxo-5-phenoxy-3,9-dioxa-6-aza-5??5-phosphaundecan-1-yl]-9H-purin-6-aminium} (2E)-but-2-enedioate; bis{propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate} (2E)-but-2-enedioate; TAF; Tenofovir alafenamide fumarate
EL9943AG5J
GS 7340
GS7340
GS-7340(Tenofovir alafenamide )
https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:90926
isopropyl ((S)-((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)(phenoxy)phosphoryl)-L-alaninate
isopropyl (2S)-2-{[(S)-{[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxy}methyl(phenoxy)phosphoryl]amino}propanoate
L-Alanine, Sp-N-[[[[(1R)-2-(6-amino-9H-purin-9-yl)-1-methylethyl]oxy]methyl]phenoxyphosphinyl]-, isopropyl ester
MFCD23843796 [MDL number]
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
propan-2-yl (2S)-2-{[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]amino}propanoate
propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate
Sp-Tenofovir-phosphonamidate, phenyl, L-alanine isopropyl ester
TAF
tenofovir alafenamida
ténofovir alafénamide
Tenofovir Alafenamide (GS-7340)
Tenofovir alafenamide;GS7340;GS 7340
tenofovirum alafenamidum
UNII:J4414G3BUK
UNII-EL9943AG5J
тенофовир алафенамид
تينوفوفير ألافيناميد
丙酚替诺福韦

SMILES

C[[email protected]](Cn1cnc2c1ncnc2N)OC[[email protected]@](=O)(N[[email protected]@H](C)C(=O)OC(C)C)Oc3ccccc3

StdInChI

InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)/t15-,16+,33+/m1/s1

StdInChIKey

LDEKQSIMHVQZJK-CAQYMETFSA-N

Molecular Formula

C21H29N6O5P

Molecular Weight

476.466

MDL Number

MFCD23843796

Properties

Appearance

White powder

Safety Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our Tenofovir alafenamide CAS 379270-37-8

Identification Methods

HNMR, HPLC

Available document

GMP, DMF

Purity

98% min

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Often used as nucleotide antiviral drugs.

Caming Pharmaceutical Ltd

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details. http://www.caming.com/tenofovir-alafenamide-cas-379270-37-8/

Watson International Ltd

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/tenofovir-alafenamide-cas-379270-37-8/