Structure of Sugammadex sodium CAS 343306-79-6

Sugammadex sodium CAS 343306-79-6

Identification

CAS Number

343306-79-6

Name

Sugammadex sodium

Synonyms

3,3′,3”,3”’,3””,3””’,3”””,3”””’-{[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56
;R)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-Hexadécahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadécaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]h
exapentacontane-5,10,15,20,25,30,35,40-octay [French] [ACD/IUPAC Name]
343306-79-6 [RN]
Octanatrium-3,3′,3”,3”’,3””,3””’,3”””,3”””’-{[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53
;R,54R,55R,56R)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31
.233,36]hexapentacontan-5,10,15,20,25,30, [German] [ACD/IUPAC Name]
Octasodium 3,3′,3”,3”’,3””,3””’,3”””,3”””’-{[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R
;,54R,55R,56R)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31
.233,36]hexapentacontane-5,10,15,20,25,30, [ACD/IUPAC Name]
Sugammadex Sodium [USAN]
D05940
MFCD09954145
Sugammadex sodium (USAN)
SUYDEX SODIUM
UNII-ERJ6X2MXV7

Molecular Structure

Structure of Sugammadex sodium CAS 343306-79-6

SMILES

C(CSC[[email protected]@H]1[[email protected]@H]2[[email protected]@H]([[email protected]]([[email protected]](O1)O[[email protected]@H]3[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]3O)O)O[[email protected]@H]4[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]4O)O)O[[email protected]@H]5[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]5O)O)O[[email protected]@H]6[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]6O)O)O[[email protected]@H]7[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]7O)O)O[[email protected]@H]8[[email protected]](O[[email protected]@H]([[email protected]@H]([[email protected]]8O)O)O[[email protected]@H]9[[email protected]](O[[email protected]](O2)[[email protected]@H]([[email protected]]9O)O)CSCCC(=O)[O-])CSCCC(=O)[O-])CSCCC(=O)[O-])CSCCC(=O)[O-])CSCCC(=O)[O-])CSCCC(=O)[O-])CSCCC(=O)[O-])O)O)C(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]

StdInChI

InChI=1S/C72H112O48S8.8Na/c73-33(74)1-9-121-17-25-57-41(89)49(97)65(105-25)114-58-26(18-122-10-2-34(75)76)107-67(51(99)43(58)91)116-60-28(20-124-12-4-36(79)80)109-69(53(101)45(60)93)118-62-30(22-126-14-6-38(83)84)111-71(55(103)47(62)95)120-64-32(24-128-16-8-40(87)88)112-72(56(104)48(64)96)119-63-31(23-127-15-7-39(85)86)110-70(54(102)46(63)94)117-61-29(21-125-13-5-37(81)82)108-68(52(100)44(61)92)115-59-27(19-123-11-3-35(77)78)106-66(113-57)50(98)42(59)90;;;;;;;;/h25-32,41-72,89-104H,1-24H2,(H,73,74)(H,75,76)(H,77,78)(H,79,80)(H,81,82)(H,83,84)(H,85,86)(H,87,88);;;;;;;;/q;8*+1/p-8/t25-,26-,27-,28-,29-,30-,31-,32-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,70-,71-,72-;;;;;;;;/m1……../s1

StdInChIKey

KMGKABOMYQLLDJ-VKHHSAQNSA-F

Molecular Formula

C72H104Na8O48S8

Molecular Weight

2178.006

Properties

Appearance

White to off-white powder or granules

Safety Data

WGK Germany

3

Specifications and Other Information of Our Sugammadex sodium CAS 343306-79-6

Identification Methods

IR, HPLC

Assay(on anhydrous and no ethanol basis)

SUG∶ 89.0%~102.0%
SUG-OH∶ 0%~5.0%
SUG+SUG-OH∶ 94.0~102.0%
Na: 7.0%~9.0%

Fe

≤30ppm

Heavy Metals

≤10ppm

Water

≤10%

Related substances(HPLC)

SUGˉIMB: ≤ 0.3%
SUG-IMC: ≤ 0.3%
SUG-IMD: ≤ 0.20%
SUG-IMJ: ≤ 0.15%
SUG-IMK: ≤ 0.15%
SUG-IM0: ≤ 0.10%
SUGˉIMR: ≤ 0,15%
Single unspecified impurity: ≤ 0.10%
Total impurities: ≤ 2.0%

Residue Solvents

Methanol: ≤300ppm
Ethanol: ≤50000ppm
DMF: ≤100ppm
DMSO: ≤500ppm

Microbiological examination

TAMC: ≤ 1000CFU/g(max.acceptable count=2000)

TYMC: ≤ 100CFU/g(max.acceptable count=200)

Bacterial endotoxin

≤0.3EU/mg

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Sodium Glucosamine is used to reverse neuromuscular blockade after administration of a non-depolarizing neuromuscular blocker such as vecuronium or rocuronium.

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details. http://www.caming.com/sugammadex-sodium-cas-343306-79-6/ This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/sugammadex-sodium-cas-343306-79-6/