Structure of Sibutramine hydrochloride monohydrate CAS 125494-59-9

Sibutramine hydrochloride monohydrate CAS 125494-59-9

Identification

CAS Number

125494-59-9, 84485-00-7, 10665-56-0

Name

Sibutramine hydrochloride monohydrate

Molecular Structure

Structure of Sibutramine hydrochloride monohydrate CAS 125494-59-9

Synonyms

1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
(±)-1-(p-Chlorophenyl)-a-isobutyl-N,N-dimethylcyclobutanemethylamine hydrochloride monohydrate
1-[1-(4-Chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrochloride hydrate
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, hydrate (1:1:1)
Sibutramine Hydrochloride
1-(4-Chlorophenyl)-N,N-dimethyl-¦Á-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrate hydrochloride
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride
Meridia
Reductil

MDL Number

MFCD04039806

Molecular Formula

C17H26ClN·HCl·H2O

Molecular Weight

334.32

Properties

Appearance

Off-white to white crystalline powder

Solubility

DMSO: >30 mg/mL
H2O: insoluble

Melting Point

190-200 ºC

Flash Point

161 °C

Boiling Point

342.6 °C at 760 mmHg

Safety Data

Personal Protective Equipment

Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

WGK Germany

3

Specifications and Other Information of Our Sibutramine hydrochloride monohydrate CAS 125494-59-9

Assay

98%min

Identification Methods

IR

Assay

98% min

TLC

One spot max

Water

5.0%-6.5%

PH

4.0-6.0

Heavy Metals

20 ppm max

Residue on Ignition

0.1% max

Biochem/Physiol Actions

Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.

Productivity

500kg-1000kg/month

General View of Doccuments

Sibutramine hydrochloride monohydrate CAS 125494-59-9 IR

Sibutramine hydrochloride monohydrate CAS 125494-59-9 IR

Storage

Room temprature

Watson-Int Link

http://watson-int.com/Somatotropin_CAS_12629-01-5.html