Sibutramine hydrochloride monohydrate CAS 125494-59-9
Identification
CAS Number
125494-59-9, 84485-00-7, 10665-56-0
Name
Sibutramine hydrochloride monohydrate
Molecular Structure
Synonyms
1-(4-Chlorophenyl)-N,N-dimethyl-alpha-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
(±)-1-(p-Chlorophenyl)-a-isobutyl-N,N-dimethylcyclobutanemethylamine hydrochloride monohydrate
1-[1-(4-Chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrochloride hydrate
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethylbutan-1-amine hydrochloride hydrate
cyclobutanemethanamine, 1-(4-chlorophenyl)-N,N-dimethyl-α-(2-methylpropyl)-, hydrochloride, hydrate (1:1:1)
Sibutramine Hydrochloride
1-(4-Chlorophenyl)-N,N-dimethyl-¦Á-(2-methylpropyl)cyclobutanemethanamine hydrochloride monohydrate
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-1-butanamine hydrate hydrochloride
1-[1-(4-chlorophenyl)cyclobutyl]-N,N,3-trimethyl-butan-1-amine hydrate hydrochloride
Meridia
Reductil
MDL Number
MFCD04039806
Molecular Formula
C17H26ClN·HCl·H2O
Molecular Weight
334.32
Properties
Appearance
Off-white to white crystalline powder
Solubility
DMSO: >30 mg/mL
H2O: insoluble
Melting Point
190-200 ºC
Flash Point
161 °C
Boiling Point
342.6 °C at 760 mmHg
Safety Data
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany
3
Specifications and Other Information of Our Sibutramine hydrochloride monohydrate CAS 125494-59-9
Assay
98%min
Identification Methods
IR
Assay
98% min
TLC
One spot max
Water
5.0%-6.5%
PH
4.0-6.0
Heavy Metals
20 ppm max
Residue on Ignition
0.1% max
Biochem/Physiol Actions
Sibutramine is a serotonin and noradrenaline reuptake inhibitor (SNRI). It is an antiobesity drug, which decreases calorie intake and increases energy expanditure. Sibutramine antagonizes MPTP-induced dopamine depletion in mouse brain.
Productivity
500kg-1000kg/month
General View of Doccuments
Storage
Room temprature
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