Structure of (S)-Amlodipine CAS 103129-82-4

(S)-Amlodipine CAS 103129-82-4

Identification

CAS Number

103129-82-4

Name

(S)-Amlodipine

Synonyms

(S)-amlodipine
3,5-pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-
3-Ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
amlodipinum
(-)-(s)-Amlodipine
(4S)-; l-Amlodipine; Levoamlodipine Besylate; (S)-Amlodipine
(4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
Amlodipine
Levamlodipine
Levoamlodipine
Levoamlodipine Besylate

Molecular Structure

Structure of (S)-Amlodipine CAS 103129-82-4

SMILES

Clc1ccccc1[C@H]2C(=C(/N/C(=C2/C(=O)OCC)COCCN)C)\C(=O)OC

StdInChI

InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1

StdInChIKey

HTIQEAQVCYTUBX-KRWDZBQOSA-N

Molecular Formula

C20H25N2O5Cl

Molecular Weight

408.88

Properties

Appearance

Off white to white powder

Solubility

Free soluble in methanol and ethanol and slightly soluble in water

Flash Point

272.617 °C

Boiling Point

527.161°C at 760 mmHg

Density

1.227g/ml

Safety Data

Personal Protective Equipment

Eyeshields, Gloves

Specifications and Other Information of Our (S)-Amlodipine CAS 103129-82-4

Assay

98.5%min

Optical Purity

98.5%min

Identifications

IR, HPLC

Optical Rotation

-24.2~-28.3°

Water

5.5% max

Residual Solvents

Ethanol: 0.5% max

Particle Size

80 mesh max

Related Substances

1.0% max

Residue on Ignition

0.1% max

Heavy Metals

20ppm max

Productivity

500kg/month

Storage

Room temperature away from light

Known Application

Lowering blood pressure, used for hypertension, angina, cardiovascular disease.

Watson-Int Link

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