(S)-Amlodipine CAS 103129-82-4
Identification
CAS Number
103129-82-4
Name
(S)-Amlodipine
Synonyms
(S)-amlodipine
3,5-pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, (4S)-
3-Ethyl 5-methyl (4S)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
amlodipinum
(-)-(s)-Amlodipine
(4S)-; l-Amlodipine; Levoamlodipine Besylate; (S)-Amlodipine
(4S)-2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
Amlodipine
Levamlodipine
Levoamlodipine
Levoamlodipine Besylate
Molecular Structure
SMILES
Clc1ccccc1[[email protected]]2C(=C(/N/C(=C2/C(=O)OCC)COCCN)C)\C(=O)OC
StdInChI
InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/t17-/m0/s1
StdInChIKey
HTIQEAQVCYTUBX-KRWDZBQOSA-N
Molecular Formula
C20H25N2O5Cl
Molecular Weight
408.88
Properties
Appearance
Off white to white powder
Solubility
Free soluble in methanol and ethanol and slightly soluble in water
Flash Point
272.617 °C
Boiling Point
527.161°C at 760 mmHg
Density
1.227g/ml
Safety Data
Personal Protective Equipment
Eyeshields, Gloves
Specifications and Other Information of Our (S)-Amlodipine CAS 103129-82-4
Assay
98.5%min
Optical Purity
98.5%min
Identifications
IR, HPLC
Optical Rotation
-24.2~-28.3°
Water
5.5% max
Residual Solvents
Ethanol: 0.5% max
Particle Size
80 mesh max
Related Substances
1.0% max
Residue on Ignition
0.1% max
Heavy Metals
20ppm max
Productivity
500kg/month
Storage
Room temperature away from light
Known Application
Lowering blood pressure, used for hypertension, angina, cardiovascular disease.
