Structure of (S)-1-Boc-3-hydroxypiperidine CAS 143900-44-1

(S)-1-Boc-3-hydroxypiperidine CAS 143900-44-1

Identification

CAS Number

161265-03-8

Name

(S)-1-Boc-3-hydroxypiperidine

Synonyms

(3S)-3-Hydroxy-1-pipéridinecarboxylate de 2-méthyl-2-propanyle [French] [ACD/IUPAC Name]
(S)-1-BOC-3-HYDROXYPIPERIDINE
(S)-N-Boc-3-hydroxy piperidine
(S)-tert-Butyl 3-hydroxypiperidine-1-carboxylate
143900-44-1 [RN]
1-Piperidinecarboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester, (3S)- [ACD/Index Name]
2-Methyl-2-propanyl (3S)-3-hydroxy-1-piperidinecarboxylate [ACD/IUPAC Name]
2-Methyl-2-propanyl-(3S)-3-hydroxy-1-piperidincarboxylat [German] [ACD/IUPAC Name]
MFCD04115307 [MDL number]
tert-butyl (3S)-3-hydroxypiperidine-1-carboxylate
tert-Butyl-(3S)-3-hydroxypiperidin-1-carboxylat
(3S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine
(3S)-3-Hydroxypiperidine N-BOC protected
(3S)-3-Hydroxypiperidine, N-BOC protected
(S)-1-Boc-3-HydroxylPiperidine
(S)-1-Boc-3-hydroxypiperidine?
(S)-1-BOC-Piperidin-3-ol
(S)-1-N-Boc-3-Hydroxypiperidine
(S)-1-N-Boc-3-Hydroxy-piperidine
(S)-1-N-Boc-3-Hydroxypiperidine (en)
(S)-3-Hydroxypiperidine, N-BOC protected
(S)-3-Hydroxy-piperidine-1-carboxylic acid tert-butyl ester
(S)-N-Boc-3-hydroxypiperidine
(s)-n-tert-butoxycarbonyl-3-hydroxypiperidine
[143900-44-1]
143900-41-1 [RN]
14390-44-1 [RN]
2-[(1-Methyl-3-piperidinyl)thio]-3-phenylquinoline hydrochloride
85275-44-1 [RN]
85275-45-2 [RN]
93286-22-7 [RN]
BR-39029
http://en.atomaxchem.com/143900-44-1.html
Ibrutinib Interm 0441
OR-6241
PS-5187
S)-1-Boc-3-hydroxypiperidine
S-1-BOC-3-Hydroxy-piperidine
tert-Butyl (3S)-3-hydroxypiperidine-1-carboxylate, (3S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine
tert-Butyl (3S)-3-hydroxypiperidine-1-carboxylate; (3S)-1-(tert-Butoxycarbonyl)-3-hydroxypiperidine
tert-butyl (S)-3-hydroxypiperidine-1-carboxylate
TL8000962

SMILES

CC(C)(C)OC(=O)N1CCC[[email protected]@H](C1)O

StdInChI

InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-5-8(12)7-11/h8,12H,4-7H2,1-3H3/t8-/m0/s1

StdInChIKey

UIJXHKXIOCDSEB-QMMMGPOBSA-N

Molecular Formula

C10H19NO3

Molecular Weight

201.263

MDL Number

MFCD04115307

Properties

Appearance

White to off-white solid

Safety Data

Symbol

exclamation-mark-jpgGHS07

Signal Word

Warning

Hazard statements

H315 – H319 – H335

Precautionary Statements

P302 + P352 – P305 + P351 + P338

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our (S)-1-Boc-3-hydroxypiperidine CAS 143900-44-1

Identification Methods

IR, HPLC, GC

Chiral purity

99.5% min

Chemical purity

99.5% min

Assay

97.0%-103.0%

Water

≤0.5%

Methanol(GC)

≤50ppm

Ethanol(GC)

≤50ppm

DCM(GC)

≤500ppm

Impurity purity

3-Hydroxypiperidine

≤0.1%

3-Hydroxypyridine

≤0.2%

1-Boc-3-piperidone

≤0.1%

1-Boc-4-hydroxypiperidine

≤0.1%

1.96RRT

≤0.2%

Any Unspecified impurity

≤0.08%

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Used as an intermediate for ibrutinib.

General View of Documents

HPLC of (S)-1-Boc-3-hydroxypiperidine CAS 143900-44-1
HPLC of (S)-1-Boc-3-hydroxypiperidine CAS 143900-44-1

This product is developed by our R&D company Caming Pharmaceutical Ltd (https://www.caming.com/).

This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).