Structure of Rebamipide CAS 90098-04-7

Rebamipide CAS 90098-04-7

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

90098-04-7

Name

Rebamipide

Synonyms

(±)-a-(p-Chlorobenzamido)-1,2-dihydro-2-oxo-4-quinolinepropionic acid
2-(4-Chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid
4-Quinolinepropanoic acid, α-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo- [ACD/Index Name]
4-quinolinepropanoic acid, α-[(4-chlorobenzoyl)amino]-2-hydroxy-
90098-04-7 [RN]
a-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
Mucosta [Trade name]
N-(4-Chlorbenzoyl)-3-(2-oxo-1,2-dihydro-4-chinolinyl)alanin [German] [ACD/IUPAC Name]
N-(4-Chlorobenzoyl)-3-(2-hydroxyquinolin-4-yl)alanine
N-(4-Chlorobenzoyl)-3-(2-oxo-1,2-dihydro-4-quinoléinyl)alanine [French] [ACD/IUPAC Name]
N-(4-Chlorobenzoyl)-3-(2-oxo-1,2-dihydro-4-quinolinyl)alanine [ACD/IUPAC Name]
N-(4-Chlorobenzoyl)-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine
Proamipide
Rebamipida [Spanish] [INN]
Rebamipide [INN] [JAN] [Wiki]
rébamipide [French] [INN]
Rebamipidum [Latin] [INN]
UNII:LR583V32ZR
ребамипид [Russian] [INN]
ريباميبيد [Arabic] [INN]
瑞巴派特 [Chinese] [INN]
(±)-2-(4-CHLOROBENZOYLAMINO)-3-(2(1H)-QUINOLINON-4-YL)-PROPIONIC ACID
?-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid
[90098-04-7]
139344-42-6 [RN]
2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid
2-(4-Chlorobenzamido)-3-[2(1H)-quinolinon-4-yl]propionic Acid
2-(4-chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)Propanoic acid
2-(4-Chlorobenzoylamino)-3-(1,2-dihydro-2-oxo-4-quinolyl)propionic acid
2-(4-chlorobenzoylamino)-3-(2(1H)-quinolinon-4-yl)propionic acid
2-(4-Chloro-benzoylamino)-3-(2-oxo-1,2-dihydro-quinolin-4-yl)-propionic acid
2-[(4-chlorobenzoyl)amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
2-[(4-chlorophenyl)carbonylamino]-3-(2-oxidanylidene-1H-quinolin-4-yl)propanoic acid
2-[(4-chlorophenyl)carbonylamino]-3-(2-oxo(4-hydroquinolyl))propanoic acid
2-[(4-chlorophenyl)formamido]-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid
2-[[(4-chlorophenyl)-oxomethyl]amino]-3-(2-oxo-1H-quinolin-4-yl)propanoic acid
4-Quinolinepropanoicacid, a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-
4-Quinolinepropanoicacid,a-[(4-chlorobenzoyl)amino]-1,2-dihydro-2-oxo-
C052785
MFCD00866895
MFCD11114396
Mucosta;OPC12759;Proamipide;Rebagen
N-[(4-chlorophenyl)carbonyl]-3-(2-hydroxyquinolin-4-yl)alanine
N-[(4-chlorophenyl)carbonyl]-3-(2-oxo-1,2-dihydroquinolin-4-yl)alanine
OPC 12759 hydrate
OPC12759
Pharmakon1600-01505310
Pramipide
Rebagen
Rebapimide
VC2518500
α-[(4-Chlorobenzoyl)amino]-1,2-dihydro-2-oxo-4-quinolinepropanoic acid

Molecular Structure

Structure of Rebamipide CAS 90098-04-7

Structure of Rebamipide CAS 90098-04-7

SMILES

c1ccc2c(c1)c(cc(=O)[nH]2)CC(C(=O)O)NC(=O)c3ccc(cc3)Cl

StdInChI

InChI=1S/C19H15ClN2O4/c20-13-7-5-11(6-8-13)18(24)22-16(19(25)26)9-12-10-17(23)21-15-4-2-1-3-14(12)15/h1-8,10,16H,9H2,(H,21,23)(H,22,24)(H,25,26)

StdInChIKey

ALLWOAVDORUJLA-UHFFFAOYSA-N

Molecular Formula

C19H15ClN2O4

Molecular Weight

370.07

MDL Number

MFCD11114396

Properties

Appearance

White crystalline powder

Safety Data

Symbol

exclamation-mark-jpgGHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301 + P310

Personal Protective Equipment

Eyeshields, Faceshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

RIDADR

UN 2811 6.1 / PGIII

WGK Germany

3

RTECS

VC2518500

Specifications and Other Information of Our Rebamipide CAS 90098-04-7

Standard

Enterprise standard

Identification Methods

HPLC,HNMR

Assay

99%min

Chlorine content

0.04%max

Heavy Metals

10ppm max

Related substances

0.5%max

Loss on Drying

2%max

Ignition residue

0.1%max

Methanol

0.3%max

Ethanol

0.5%max

Dichloromethane

0.06%max

Acetic acid

0.5%max

Package

According to customer requirements to packaging

Storage

Under the room temperature and away from light.

Application

Commonly used in new anti-ulcer drugs.
Rebamipide is a gastric mucosal protective agent, can increase gastric mucosal blood flow, prostaglandin E2 synthesis and gastric mucus secretion, promote epidermal growth factor and its receptor expression, prevention of ulcer occurrence and promote ulcer healing. Studies have shown that it is effective for a variety of experimental gastric ulcer, can promote gastric mucosal prostaglandin production, protect the gastric mucosa from various ulcer-causing factors, suitable for the treatment of gastric ulcer, acute gastritis, acute exacerbation of chronic gastritis, stomach Mucosal lesions, a higher clinical value.

Links

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/rebamipide-cas-90098-04-7/

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/rebamipide-cas-90098-04-7/