635702-64-6 Pazopanib hydrochloride - Watsonnoke Scientific Ltd

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

635702-64-6

Name

Pazopanib hydrochloride

Synonyms

5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzenesulfonamide hydrochloride (1:1) [ACD/IUPAC Name]
5-({4-[(2,3-Diméthyl-2H-indazol-6-yl)(méthyl)amino]-2-pyrimidinyl}amino)-2-méthylbenzènesulfonamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]-2-pyrimidinyl}amino)-2-methylbenzolsulfonamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
635702-64-6 [RN]
Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1) [ACD/Index Name]
GW786034B
GW-786034B
Pazopanib Hydrochloride [USAN]
Votrient [Trade name]
[635702-64-6]
444731-52-6 [RN]
5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide hydrochloride
5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride
5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide hydrochloride
5-[[4-[(2, 3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2- methylbenzenesulfonamide;hydrochloride
5-[[4-[(2,3-dimethyl-6-indazolyl)-methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide hydrochloride
5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide and hydron and chloride
5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide;hydrochloride
5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide HCl
5-{4-[(2,3-Dimethyl-2H-indazol-6-yl)-methyl-amino]-pyrimidin-2-ylamino}-2-methyl-benzenesulfonamide hydrochloride
Armala
GW 786034
GW786034
GW786034;Votrient;Armala;GW 786034;GW-786034
GW786034GW786034, VOTRIENT
HYDROGEN PAZOPANIB CHLORIDE
MFCD12546138 [MDL number]
Pazopanib
Pazopanib (GW-786034)
Pazopanib (Hydrochloride)
Pazopanib HCL
Pazopanib HCl (GW786034 HCl)
pazopanib monohydrochloride
Pazopanib, Votrient, GW786034B, GW 786034, GW-786034
UNII:33Y9ANM545
UNII-33Y9ANM545

Molecular Structure

Structure of Pazopanib hydrochloride CAS 635702-64-6

SMILES

Cc1ccc(cc1S(=O)(=O)N)Nc2nccc(n2)N(C)c3ccc4c(n(nc4c3)C)C.Cl

StdInChI

InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H

StdInChIKey

MQHIQUBXFFAOMK-UHFFFAOYSA-N

Molecular Formula

C21H23N7O2S.HCl

Molecular Weight

473.98

Properties

Appearance

White to off-white powder

Safety Data

WGK Germany

Specifications and Other Information of Our Pazopanib hydrochloride CAS 635702-64-6

Standard

Enterprise standard

Identification Methods

HPLC,XRD

Purity

99%min

Heavy Metals

10 ppm max

Loss on Drying

0.5% max

Residue on Ignition

0.2% max

Single Impurity

0.2% max

Total Impurities

0.5% max

Package

According to customer requirements to packaging

Manufacturing Capacity

KG Scale

Storage

Under room temperature away from light

Application

Palazepine Hydrochloride is a novel type of oral angiogenesis inhibitor that can interfere with the angiogenesis required for the survival and growth of stubborn tumors, targeting the role of vascular endothelial growth factor receptor (VEGFR), by inhibiting the new blood supply to the tumor Angiogenesis and work. Suitable for the treatment of advanced renal cell carcinoma (a type of renal cell carcinoma found in renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer and non-small cell lung cancer (NSCLC).

General View of Documents

Pazopanib hydrochloride CAS 635702-64-6 HPLC

Pazopanib hydrochloride CAS 635702-64-6 XRD

Pazopanib hydrochloride CAS 635702-64-6