Nalfurafine hydrochloride CAS 152658-17-8
Identification
Properties
Safety Data
Specifications & Other Information
Links
Identification
CAS Number
152658-17-8
Name
Nalfurafine hydrochloride
Synonyms
(2E)-N-[(5α,6β)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]-3-(3-furyl)-N-methylacrylamide hydrochloride (1:1) [ACD/IUPAC Name]
(2E)-N-[(5α,6β)-17-(Cyclopropylmethyl)-3,14-dihydroxy-4,5-epoxymorphinan-6-yl]-3-(3-furyl)-N-methylacrylamidhydrochlorid (1:1) [German] [ACD/IUPAC Name]
(2E)-N-[(5α,6β)-17-(Cyclopropylméthyl)-3,14-dihydroxy-4,5-époxymorphinane-6-yl]-3-(3-furyl)-N-méthylacrylamide, chlorhydrate (1:1) [French] [ACD/IUPAC Name]
152658-17-8 [RN]
2-Propenamide, N-[(5α,6β)-17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]-3-(3-furanyl)-N-methyl-, (2E)-, hydrochloride (1:1) [ACD/Index Name]
Nalfurafine hydrochloride [USAN]
Nalfurafine (hydrochloride)
Remitch hydrochloride
TRK-820 hydrochloride
UNII-25CC4N0P8J
Molecular Structure
SMILES
CN([C@@H]1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3CC6CC6)O)C(=O)/C=C/C7=COC=C7.Cl
StdInChI
InChI=1S/C28H32N2O5.ClH/c1-29(23(32)7-4-18-9-13-34-16-18)20-8-10-28(33)22-14-19-5-6-21(31)25-24(19)27(28,26(20)35-25)11-12-30(22)15-17-2-3-17;/h4-7,9,13,16-17,20,22,26,31,33H,2-3,8,10-12,14-15H2,1H3;1H/b7-4+;/t20-,22-,26+,27+,28-;/m1./s1
StdInChIKey
DJSFYNINGIMKAG-FQJQBBMWSA-N
Molecular Formula
C28H33ClN2O5
Molecular Weight
513.025
Properties
Appearance
White powder
Specifications and Other Information of Our Nalfurafine hydrochloride CAS 152658-17-8
Standard
Enterprise standard
Identification Methods
HNMR/HPLC
Purity
98%min
Heavy Metal
10ppm
Storage
Under the room temperature and away from light
Application
Nalfurafine hydrochloride was launched on March of 2009 in Japan as the first in class non-narcotic opioid drug for intractable itch caused by hemodialysis. It showed significant opioid agonist acti vity and induced neither aversion nor preference in rats on the CPP (Conditioned Place Preference) test. A new therapeutic agent for the treatment of uremic pruritus in hemodialysis patients.
Links
Caming Pharmaceutical Ltd
This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/nalfurafine-hydrochloride-cas-152658-17-8/
Watson International Ltd
This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/nalfurafine-hydrochloride-cas-152658-17-8/