Mirtazapine CAS 61337-67-5 (85650-52-8)
Identification
CAS Number
61337-67-5 or 85650-52-8
Name
Mirtazapine
Synonyms
2-Methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin
2-Methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepin
2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
2-méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine
2-Méthyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazépine
Avanza
mirtazapina
mirtazapinum
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Remeron
Zispin
(14bR)-2-methyl-1,2,3,4,10,14b-hexahydropyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
(rs)-1,2,3,4,10,14b-hexahydro-2-methylpyrazino-(2,1-a)pyrido(2,3-c)(2)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino(2,1-a)pyrido(2,3-c)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c](2)benzazepine
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
2-Methyl-1,2,3,4,9,13b-hexahydro-2,4a,5-triaza-tribenzo[a,c,e]cycloheptene
5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8(13),9,11,16,18-hexaene
5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(19),8(13),9,11,15,17-hexaene
6-AZAMIANSERIN
Azamianserin
Mepirzapin
mepirzepine
Mirtazanine
Mirtazepine
Mirtazipine
Norset
Promyrtil
Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-
Pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-, (±)-
Remergil
Remergon
Remeron
Rexer
Molecular Structure
SMILES
CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4
StdInChI
InChI=1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
StdInChIKey
RONZAEMNMFQXRA-UHFFFAOYSA-N
Molecular Formula
C17H19N3
Molecular Weight
265.35
MDL Number
MFCD00865427
EINECS
288-060-6
Properties
Appearance
A white or almost white crystalline powder
Solubility
Freely soluble in methanol and in toluene, soluble in ethylether, sparingly soluble in hexane, practically insoluble in water.
Safety Data
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
WGK Germany
3
Specifications and Other Information of Our Mirtazapine CAS 61337-67-5 (85650-52-8)
Standard
USP
Identification
IR
Assay
98%-102% (anhydrate substance)
Water
1.0%-3.5%
Residue on Ignition
0.1% max
Heavy Metals
10ppm max
Residual Solvents
Dimethyl sulfoxide: 880ppm max
Tetrahydrofuran: 720ppm max
Toluene: 890ppm max
Chloroform: 60ppm max
N-heptane: 500ppm max
Ethanol: 5000ppm max
Impurities
Impurity A: 0.10% max
Impurity B: 0.10% max
Impurity C: 0.10% max
Impurity D: 0.10% max
Impurity E: 0.10% max
Individual unspecified impurity: 0.10% max
Total impurities: 0.50% max
Package
25kg/drum
Manufacturing Capacity
1 MT/year
Storage
Under room temperature,away from light
Application
Mirtazapine (brand names: Avanza (AU, NZ), Axit (AU), Mirtaz (IN, IE†), Mirtazon (AU), Remeron (AU, CA, HK, IL, NZ†, RU, SG, ZA, US), Zispin (IE, UK); where † indicates discontinued products) is a noradrenergic and specific serotonergic antidepressant (NaSSA) that was introduced by Organon International in the United States in 1996 and is used primarily in the treatment of depression. It is also commonly used as an anxiolytic, hypnotic, antiemetic and appetite stimulant. In terms of structure, mirtazapine can also be classified as a tetracyclic antidepressant (TeCA).
Watson-Int Link
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