Lubiprostone CAS 333963-40-9
Identification
Properties
Safety Data
Specifications & Other Information
Links
Identification
CAS Number
333963-40-9
Name
Lubiprostone
Synonyms
(11α,15R)-16,16-Difluor-15-hydroxy-9-oxo-11,15-epoxyprostan-1-säure [German] [ACD/IUPAC Name]
(11α,15R)-16,16-Difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid [ACD/IUPAC Name]
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-Difluorpentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyr-5-yl]heptansäure [German]
Acide (11α,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-époxyprostan-1-oïque [French] [ACD/IUPAC Name]
acide 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoïque [French]
Lubiprostone [Wiki]
Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11α,15R)- [ACD/Index Name]
(-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta (b)pyran-5-yl)heptanoic acid
(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid
[118583-35-0]
[136790-76-6]
118583-35-0 [RN]
136790-76-6 [RN]
333963-40-9 [RN]
333963-40-9; 136790-76-6
7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid
7-[(1R,4R,6R,9R)-4-(1,1-Difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-keto-3,4,4a,5,7,7a-hexahydrocyclopenta[e]pyran-5-yl]enanthic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[e]pyran-5-yl]heptanoic acid
Amitiza [Wiki]
Amitiza®
Amitiza®|SPI-0211
Amitiza, RU-0211, SPI-0211
LB-BPK
Lubiprostone [USAN] [USAN]
MFCD08444045
Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)- [ACD/Index Name]
UNII-7662KG2R6K
Molecular Structure
SMILES
CCCCC([C@]1(CC[[email protected]]2[[email protected]](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F
StdInChI
InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1
StdInChIKey
WGFOBBZOWHGYQH-MXHNKVEKSA-N
Molecular Formula
C20H32F2O5
Molecular Weight
390.46
Properties
Appearance
white powder
Melting Point
213 °C
Specifications and Other Information of Our Lubiprostone CAS 333963-40-9
Standard
Enterprise standard
Identification Methods
HPLC
Purity
96%~102%
Water
1.0% max
Ethyl acetate
0.5%max
n-Heptane
0.5%max
Total Impurities
1.5%max
Storage
Stored below 5℃ for long time.
Application
It is a limitation of chloride channel activator, selectively activated located in the gastrointestinal tract epithelial type 2 chloride channel (CIC-2) on the tip of the lumen of the membrane, increasing intestinal fluid secretion and intestinal motility, thereby increased bowel movements, reduce the symptoms of chronic idiopathic constipation, and does not change in plasma sodium and potassium concentrations.
Links
Caming Pharmaceutical Ltd
This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/lubiprostone-cas-333963-40-9/
Watson International Ltd
This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/lubiprostone-cas-333963-40-9/
