Structure of Lubiprostone CAS 333963-40-9

Lubiprostone CAS 333963-40-9

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

333963-40-9

Name

Lubiprostone

Synonyms

(11α,15R)-16,16-Difluor-15-hydroxy-9-oxo-11,15-epoxyprostan-1-säure [German] [ACD/IUPAC Name]
(11α,15R)-16,16-Difluoro-15-hydroxy-9-oxo-11,15-epoxyprostan-1-oic acid [ACD/IUPAC Name]
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-Difluorpentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyr-5-yl]heptansäure [German]
Acide (11α,15R)-16,16-difluoro-15-hydroxy-9-oxo-11,15-époxyprostan-1-oïque [French] [ACD/IUPAC Name]
acide 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl]heptanoïque [French]
Lubiprostone [Wiki]
Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11α,15R)- [ACD/Index Name]
(-)-7-((2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta (b)pyran-5-yl)heptanoic acid
(2R,4aR,5R,7aR)-2-(1,1-Difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-heptanoic acid
[118583-35-0]
[136790-76-6]
118583-35-0 [RN]
136790-76-6 [RN]
333963-40-9 [RN]
333963-40-9; 136790-76-6
7-((2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxooctahydrocyclopenta[b]pyran-5-yl)heptanoic acid
7-[(1R,4R,6R,9R)-4-(1,1-Difluoropentyl)-4-hydroxy-8-oxo-5-oxabicyclo[4.3.0]non-9-yl]heptanoic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-keto-3,4,4a,5,7,7a-hexahydrocyclopenta[e]pyran-5-yl]enanthic acid
7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[e]pyran-5-yl]heptanoic acid
Amitiza [Wiki]
Amitiza®
Amitiza®|SPI-0211
Amitiza, RU-0211, SPI-0211
LB-BPK
Lubiprostone [USAN] [USAN]
MFCD08444045
Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11α)- [ACD/Index Name]
UNII-7662KG2R6K

Molecular Structure

Structure of Lubiprostone CAS 333963-40-9

Structure of Lubiprostone CAS 333963-40-9

SMILES

CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F

StdInChI

InChI=1S/C20H32F2O5/c1-2-3-11-19(21,22)20(26)12-10-15-14(16(23)13-17(15)27-20)8-6-4-5-7-9-18(24)25/h14-15,17,26H,2-13H2,1H3,(H,24,25)/t14-,15-,17-,20-/m1/s1

StdInChIKey

WGFOBBZOWHGYQH-MXHNKVEKSA-N

Molecular Formula

C20H32F2O5

Molecular Weight

390.46

Properties

Appearance

white powder

Melting Point

213 °C

Specifications and Other Information of Our Lubiprostone CAS 333963-40-9

Standard

Enterprise standard

Identification Methods

HPLC

Purity

96%~102%

Water

1.0% max

Ethyl acetate

0.5%max

n-Heptane

0.5%max

Total Impurities

1.5%max

Storage

Stored below 5℃ for long time.

Application

It is a limitation of chloride channel activator, selectively activated located in the gastrointestinal tract epithelial type 2 chloride channel (CIC-2) on the tip of the lumen of the membrane, increasing intestinal fluid secretion and intestinal motility, thereby increased bowel movements, reduce the symptoms of chronic idiopathic constipation, and does not change in plasma sodium and potassium concentrations.

Links

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/lubiprostone-cas-333963-40-9/

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/lubiprostone-cas-333963-40-9/