Levothyroxine sodium CAS 55-03-8(25416-65-3)

Identification

CAS Number

55-03-8(25416-65-3)

Name

Levothyroxine sodium

Synonyms

Levothyroxine Sodium [INN] [USAN]
(2S)-2-Amino-3-[4-(4-hydroxy-3,5-diiodophénoxy)-3,5-diiodophényl]propanoate de sodium [French] [ACD/IUPAC Name]
200-221-4 [EINECS]
216-080-7 [EINECS]
453
55-03-8 [RN]
Eltroxin [Trade name]
Euthyrox [Trade name]
L-3,3′,5,5′-Tetraiodothyronine Sodium Salt
Levaxin [Trade name]
Levothroid [Trade name]
lévothyroxine sodique [French] [INN]
levothyroxinum natricum [Latin] [INN]
levotiroxina de sodio [Spanish] [INN]
Levotiroxina sodica [Spanish] [INN]
Levoxyl [Trade name]
L-Thyroxine monosodium salt
L-Thyroxine sodium salt [USP]
L-Tyrosine, O- (4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, sodium salt (1:1) [ACD/Index Name]
Natrium-(2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodphenoxy)-3,5-diiodphenyl]propanoat [German] [ACD/IUPAC Name]
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine Monosodium Salt
Oroxine [Trade name]
Sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate [ACD/IUPAC Name]
Sodium Levothyroxine
Sodium l-thyroxin
SODIUM L-THYROXINE
Synthroid [Trade name]
Thyro-Tabs [Trade name]
левотироксин натрия [Russian] [INN]
ليفوثيروكسين صوديوم [Arabic] [INN]
左甲状腺素钠 [Chinese] [INN]
[55-03-8]
3,3´,5,5´-Tetraiodo-L-thyronine sodium salt
3,3′,5,5′-Tetraiodo-L-thyronine, sodium salt
3,3?,5,5?-Tetraiodo-L-thyronine sodium salt
5721845 [Beilstein]
Dathroid
DL-THYROXINE SODIUM SALT
EINECS 200-221-4
EINECS 216-080-7
Laevoxin
Letter
Levoroxine
Levo-T
Levothyroid
Levothyrox
levothyroxine sodique
Levothyroxine sodique [INN-French]
Levothyroxinesodium
Levothyroxin-natrium
levothyroxinum natricum
Levothyroxinum natricum [INN-Latin]
levotiroxina de sodio
Levotiroxina sodica [INN-Spanish]
Levoxine
L-thyroxine sodium
L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-, monosodium salt
MFCD00002596
Novothyrox
Powdered Thyroid
QA-1528
Ro-thyroxine
Roxstan
sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propanoate
sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodo-phenoxy)-3,5-diiodo-phenyl]propionate
sodium (S)-2-amino-3-(4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)propanoate
SODIUM LEVOTHYROXINE(1-)
sodium O-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosinate
Sodium thyroxin
Sodium thyroxinate
Sodium thyroxine
Sodiumlevothyroxine
Sodium-L-thyroxine
Soloxine
ST5330577
Synthroid sodium
Tetroid
Thyradin [Wiki]
Thyradin S
Thyrax [Wiki]
Thyroid [Wiki]
Thyrol L
Thyronamin
Thyroxevan
Thyroxin sodium
Thyroxine sodique
thyroxine sodium
THYROXINE, MONOSODIUM SALT, L-
Thyroxinum natricum
Tiroidina
tirosint
Unithroid

Molecular Structure

Structure of Levothyroxine sodium CAS 55-03-8(25416-65-3)

SMILES

c1c(cc(c(c1I)Oc2cc(c(c(c2)I)O)I)I)C[[email protected]@H](C(=O)[O-])N.[Na+]

StdInChI

InChI=1S/C15H11I4NO4.Na/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23;/h1-2,4-5,12,21H,3,20H2,(H,22,23);/q;+1/p-1/t12-;/m0./s1

StdInChIKey

YDTFRJLNMPSCFMYDALLXLXSA-M

Molecular Formula

C15H10I4NNaO4

Molecular Weight

798.852 

EINECS

200-221-4

MDL Number

MFCD06408007

Properties

Appearance

Off-white to buff colored powder

Safety Data

Personal Protective Equipment

EyeshieldsGlovestype N95 (US)type P1 (EN143) respirator filter

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our Levothyroxine sodium CAS 55-03-8(25416-65-3)

Identification Methods

HPLC

Assay

100%~103%

Specific Optical Rotation

-5 ° ~ -6 °

Water

≤11%

Related substances

Liothyronine

≤1.0%

Beta hydroxy-T 4a

≤ 0.15%

T4-Hydroxy Acetic acid

≤0.15%

N-Formyl-T4 and T4 Acetamide

≤0.15%

N-Acetyl-T 4

≤0.20%

T4-Acetici acid

≤0.30%

T4-Aldehyde

≤0.15%

T4-Benzoic Acid

≤0.15%

Individual unspecified impurity

≤0.10%

Total impurities

≤0.20%

Residual solvents

Ethanol

≤5000ppm

1-Propanol

≤5000ppm

2-propanol

≤5000ppm

lsopropyl acetate

≤5000ppm

Acetic acid content (by HPLC)

≤5000ppm

Shelf Life

1 year

Storage

Store in a closed container at room temperature at 25℃~30 ℃.

Productivity

1MT/month

Known Application

Commonly used as corticosteroid.

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details. http://www.caming.com/levothyroxine-sodium-cas-55-03-8(25416-65-3)/ This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/levothyroxine-sodium-cas-55-03-8(25416-65-3)/
Posted in APIs, Caming Pharmaceutical Ltd, Products