structure of Lefamulin CAS 1061337-51-6

Lefamulin CAS 1061337-51-6

Identification

CAS Number

1061337-51-6

Name

Lefamulin

Synonyms

(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl {[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetate [ACD/IUPAC Name]
(1S,2R,3S,4S,6R,7R,8R,14R)-3-Hydroxy-2,4,7,14-tetramethyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tetradec-6-yl-{[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanyl}acetat [German] [ACD/IUPAC Name]
{[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]sulfanyl}acétate de (1S,2R,3S,4S,6R,7R,8R,14R)-3-hydroxy-2,4,7,14-tétraméthyl-9-oxo-4-vinyltricyclo[5.4.3.01,8]tétradéc-6-yle [French] [ACD/IUPAC Name]
1061337-51-6 [RN]
21904A5386
Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester [ACD/Index Name]
lefamulina [Spanish] [INN]
léfamuline [French] [INN]
lefamulinum [Latin] [INN]
Xenleta [Trade name]
[(1S,2R,3S,4S,6R,7R,8R,14R)-4-ethenyl-3-hydroxy-2,4,7,14-tetramethyl-9-oxo-6-tricyclo[5.4.3.01,8]tetradecanyl] 2-[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]sulfanylacetate
1061337-51-6 (free base)
1061872-97-6 [RN]
62B
lefamulina
léfamuline
lefamulinum
MFCD28963989
UNII:21904A5386
UNII-21904A5386
лефамулин [Russian]
ليفامولين [Arabic]
来法莫林 [Chinese]
Less…
Validated by Experts, Validated by Users, Non-Validated, Removed by Users
9849 [DBID]
BC-3781 [DBID]
UNII-61H04Z5F9K [DBID]

SMILES

C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@@]1([C@@H](C[C@@]([C@H]([C@@H]3C)O)(C)C=C)OC(=O)CS[C@@H]4CC[C@H](C[C@H]4O)N)C

StdInChI

InChI=1S/C28H45NO5S/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27+,28+/m1/s1

StdInChIKey

KPVIXBKIJXZQJX-FCEONZPQSA-N

Molecular Formula

C28H45NO5S

Molecular Weight

507.726

MDL Number

MFCD28963989

Properties

Appearance

solid

Structure

structure of Lefamulin CAS 1061337-51-6
structure of Lefamulin CAS 1061337-51-6

Safety Data

Symbol

Signal Word

Warning

WGK Germany

3

MSDS Download

Specifications and Other Information of Our

Water

Loss on Drying

Residue on Ignition

Single Impurity

Total Impurities

Shelf Life

2 years

Storage

Under room temperature away from light

Known Application

Lefamulin is a pleuromutilin class antibiotic used to treat community-acquired bacterial pneumonia (CABP) in adult patients caused by susceptible microorganisms. To minimize the emergence of resistant bacteria and preserve the efficacy of Lefamulin and other antibiotics, it should be used only for the treatment or prevention of confirmed or highly suspected bacterial infections.

General View of Documents

This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).

This product is sold exclusively through our sales company Watson International Limited, and please click the link below for details (https://www.watson-int.com/).