L-(+)-Selenomethionine CAS 3211-76-5
Identification
Properties
Safety Data
Specifications & Other Information
Links
Identification
CAS Number
3211-76-5
Name
L-(+)-Selenomethionine
Synonyms
(2R)-2-amino-4-(methylselanyl)butanoic acid
(2R)-2-amino-4-(methylseleno)butanoic acid
(2S)-2-Amino-4-(methylseleno)butanoic acid
butanoic acid, 2-amino-4-(methylseleno)-, (2R)-
L-(+)-Selenomethionine
(S)-(+)-2-Amino-4-(methylseleno)butanoic acid
Molecular Structure
SMILES
O=C(O)[[email protected]](N)CC[Se]C
StdInChI
InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
StdInChIKey
RJFAYQIBOAGBLC-SCSAIBSYSA-N
Molecular Formula
C5H11NO2Se
Molecular Weight
196.11
MDL Number
MFCD00037210
Properties
Appearance
Off-white to white powder
Solubility
50mg in 1ml water clear soluble
Melting Point
265 ºC
Boiling Point
320.78 °C at 760 mmHg
Flash Point
147.803 °C
Safety Data
Symbol
Signal Word
Danger
Hazard Statements
Precautionary Statements
P261-P273-P301 + P310-P311-P501
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
20/21-28-45-60-61
RIDADR
UN 3283 6.1/PG 2
WGK Germany
3
RTECS
EK7713840
Specifications and Other Information of Our L-(+)-Selenomethionine CAS 3211-76-5
Assay
98.0%-102.0%
Identification Method
HNMR, MS, HPLC
Optical rotation20℃/D(C=1, 1N HCl)
+16.5°~+20°
D-Isomer content
0.05% max
Arsenic
1 ppm max
Cadmium
1 ppm max
Mercury
0.1 ppm max
Lead
3 ppm max
Water
0.5% max
Biochem/physiol Actions
Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations and interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine, caused by excessive peroxynitrite. Selenomethionine administration to cancer cell lines (MCF-7/S breast carcinoma, DU-145 prostate cancer cells and UACC-375 melanoma) results in apoptotic cell death and aberrant mitosis. These human tumor cell lines exhibited dose-dependent growth inhibition by selenomethionine in the micromolar range (45 to 130 μM), while growth inhibition of normal fibroblasts required 1 mM selenomethionine.
Productivity
1kg/month
Storage Tempeature
Transport at room temperature, long-term preservation at 0 ~ 5°
General View of Documents
Links
Apnoke Scientific Ltd
This product is developed by our sub R&D company Apnoke Scientific Ltd, and please click the link below for details.
http://www.apnoke.com/l-selenomethionine-cas-3211-76-5-2/
Watson International Ltd
This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/l-selenomethionine-cas-3211-76-5-2/