3211-76-5 L-(+)-Selenomethionine - Watson Noke Scientific

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

3211-76-5

Name

L-(+)-Selenomethionine

Synonyms

(2R)-2-amino-4-(methylselanyl)butanoic acid
(2R)-2-amino-4-(methylseleno)butanoic acid
(2S)-2-Amino-4-(methylseleno)butanoic acid
butanoic acid, 2-amino-4-(methylseleno)-, (2R)-
L-(+)-Selenomethionine
(S)-(+)-2-Amino-4-(methylseleno)butanoic acid

Molecular Structure

Structure of L-(+)-Selenomethionine CAS 3211-76-5

SMILES

O=C(O)[C@H](N)CC[Se]C

StdInChI

InChI=1S/C5H11NO2Se/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1

StdInChIKey

RJFAYQIBOAGBLC-SCSAIBSYSA-N

Molecular Formula

C5H11NO2Se

Molecular Weight

196.11

MDL Number

MFCD00037210

Properties

Appearance

Off-white to white powder

Solubility

50mg in 1ml water clear soluble

Melting Point

265 ºC

Boiling Point

320.78 °C at 760 mmHg

Flash Point

147.803 °C

Safety Data

Symbol

GHS06, GHS08, GHS09

Signal Word

Danger

Safety Statements (Europe)

20/21-28-45-60-61

RIDADR

UN 3283 6.1/PG 2

WGK Germany

RTECS

EK7713840

Specifications and Other Information of Our L-(+)-Selenomethionine CAS 3211-76-5

Assay

98.0%-102.0%

Identification Method

HNMR, MS, HPLC

Optical rotation20℃/D(C=1, 1N HCl)

+16.5°~+20°

D-Isomer content

0.05% max

Arsenic

1 ppm max

Cadmium

1 ppm max

Mercury

0.1 ppm max

Lead

3 ppm max

Water

0.5% max

Biochem/physiol Actions

Selenomethionine displays antioxidant activity and has been shown to increase the activity of glutathione peroxidase in endothelial cells. Glutathione peroxidase protects cells from oxidative damage, such as DNA strand breaks, mutations and interference with protein tyrosine-based signaling and other protein functions due to formation of 3-nitrotyrosine, caused by excessive peroxynitrite. Selenomethionine administration to cancer cell lines (MCF-7/S breast carcinoma, DU-145 prostate cancer cells and UACC-375 melanoma) results in apoptotic cell death and aberrant mitosis. These human tumor cell lines exhibited dose-dependent growth inhibition by selenomethionine in the micromolar range (45 to 130 μM), while growth inhibition of normal fibroblasts required 1 mM selenomethionine.

Productivity

1kg/month

Storage Tempeature

Transport at room temperature, long-term preservation at 0 ~ 5°

General View of Documents

L-(+)-Selenomethionine CAS 3211-76-5 HPLC

D Type Reference Sample HPLC