Glycopyrrolate CAS 596-51-0
Identification
CAS Number
596-51-0
Name
Glycopyrrolate
Synonyms
α-cyclopentylmandelic acid ester with 3-hydroxy-1,1-dimethylpyrrolidinium bromide
1-methyl-3-pyrrolidyl α-cyclopentylmandelate methobromide
1-methyl-3-pyrrolidyl α-phenyl-α-cyclopentylglycolate methobromide
3-(2-phenyl-2-cyclopentylglycoloyloxy)-1,1-dimethylpyrrolidinium bromide
3-hydroxy-1,1-dimethylpyrrolidinium bromide α-cyclopentylmandelate
AHR-504
Copyrrolate
Gastrodyn
NSC 250836
NSC 251251
NSC 251252
NVA-237
glycopyrronium bromide
Molecular Structure
SMILES
O=C(OC1CC[N+](C)(C)C1)C(O)(c2ccccc2)C3CCCC3
StdInChI
InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1
StdInChIKey
ANGKOCUUWGHLCE-UHFFFAOYSA-N
EINECS
209-887-0
Molecular Formula
C19H28NO3.Br
Molecular Weight
398.34
MDL Number
MFCD00072137
Properties
Appearance
Off-white to white crystalline powder
Solubility
H2O: ≥24 mg/mL
Melting Point
193-198 °C
Safety Data
Symbol
GHS07
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
26
WGK Germany
3
Specifications and Other Information of Our Glycopyrrolate CAS 596-51-0
Standard
USP
Assay
98.0%-100.5%
Ordinary Impurities
Single: 0.5% max
Total: 2.0% max
Related Compounds
Single: 0.1% max
Total: 0.5% max
Residual Solvents
Methyl Alcohol: 3000ppm max
Isopropyl ether: 5000ppm max
2-Butanone: 3000ppm max
n-Heptane: 5000ppm max
Particle Size: D90:≤80µm
Other Doccuments Avaiable
DMF
Identification Method
IR, HPLC
Known Application
In anesthesia, glycopyrrolate injection can be used as a preoperative medication in order to reduce salivary,tracheobronchial, and pharyngeal secretions, as well as decreasing the acidity of gastric secretion. It is also used in conjunction with neostigmine, a neuromuscular blocking reversal agent, to prevent neostigmine’s muscarinic effects such as bradycardia. It is also used to reduce excessive saliva (sialorrhea). It decreases acid secretion in the stomach and so may be used for treating stomach ulcers, in combination with other medications. Use in treating asthma and COPD has been described. It has been used topically and orally to treat hyperhidrosis.
Productivity
kg scale
Storage
2-8°C
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