Fermented β-Glucan CAS 9012-72-0

Identification

CAS Number

9012-72-0

Name

Fermented β-Glucan

Synonyms

α-D-xylo-Hexopyranose, O-β-D-glucopyranosyl-(1->4)-O(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-, (4ξ)- [ACD/Index Name]
β-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose [ACD/IUPAC Name]
β-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose [German] [ACD/IUPAC Name]
β-D-Glucopyranosyl-(1->4)-(4ξ)-β-D-xylo-hexopyranosyl-(1->4)-(4ξ)-α-D-xylo-hexopyranose [French] [ACD/IUPAC Name]
?-D-Glucan
9008-22-4 [RN]
9012-72-0 [RN]
9041-22-9 [RN]
D-GLUCAN
Glucan [Wiki]
ß-D-Glucan
β-D-Glucan
β-Glucan

SMILES

C([C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OC2[C@H](O[C@H]([C@@H]([C@H]2O)O)OC3[C@H](O[C@@H]([C@@H]([C@H]3O)O)O)CO)CO)O)O)O)O

StdInChI

InChI=1S/C18H32O16/c19-1-4-7(22)8(23)12(27)17(31-4)34-15-6(3-21)32-18(13(28)10(15)25)33-14-5(2-20)30-16(29)11(26)9(14)24/h4-29H,1-3H2/t4-,5-,6-,7-,8+,9-,10-,11-,12-,13-,14?,15?,16+,17+,18+/m1/s1

StdInChIKey

FYGDTMLNYKFZSV-URKRLVJHSA-N

Molecular Formula

C18H32O16

Molecular Weight

504.437

Properties

Appearance

White powder

Safety Data

RIDADR 

NONH for all modes of transport

WGK Germany

3

Specifications and Other Information of Our Fermented β-Glucan CAS 9012-72-0

Description

Fermented β-Glucan is a kind of glucan with every 3 unit of β-1,3 backbone binding with one unit of β-1,6 branch, forming triplex structure, the culture is collected in sea. Based on such unique triplex structure, Fermented β-Glucan can bind with several cells locus like CR3, Dectin-1, activating human immune cells, including macrophage, neutrophil, natural killer. These immune cells will stimulate the immune system to secrete cytokines (IL-1, IL-6 etc.). With state of the art fermentation processes, Fermented β-Glucan retains active ingredients of the culture and good solubility, which is a unique and novel glucan in the world. In Cosmetics, Fermented β-Glucan shows outstanding properties and efficiency, strengthening skin immunity, anti-aging, antiallergic, repairing skin, moisturizing etc., which is one of the best quality active ingredients in current cosmetics market.

Comparison to other β-glucans

ParametersFermented β-GlucanYeast β-GlucanOats β-Glucan
Solubility in waterSolubleInsolubleSoluble
Producing ProcessFermentationExtractExtract
SourceCulture from seaYeast CellCereal
Molecular Structureβ-1,6 branches
β-1,3 backbone
β-1,6 branches
β-1,3 backbone
Mix of β-1,3 and β-1,4
Percentage of β-1,3 linkage65%85%10%
Percentage of β-1,6 linkage35%15%0%
Percentage of β-1,4 linkage0%0%90%
Thermostability++++++++++
pH Stability++++++++++
Moisturizing++++++++
Antiallergic+++++++++

Functions

  1. Increase immunity
  2. Anti-aging
  3. Anti-wrinkle and fine lines
  4. Repair skin
  5. Anti-allergic and anti-inflammation
  6. Moisturize and film
  7. Promote wound healing and skin regeneration
  8. Prevent and fade striae gravidarum

Properties

1. Unique triplex structure, specifically binding with Dectin-1, CR3 etc., activating Langerhans’ cells, macrophage, neutrophil, NK, T-cells, strengthen skin immunity
2. Accelerating the proliferation of Langerhans’ cells
3. Scavenging free radicals
4. Accelerating cytokines to create AP-1, NF-1, IL-1, IL-10 and TNF-β etc.
5. Promoting the proliferation of fibroblast and synthesis of collagen and elastin
6. Boosting the concentration of leukin, cytokinin and special antibodies (such as IgM)
7. Degrading metalloprotease, which are enzymes hydrolyzing collagen and elastin
8. Regaining balance of TH1/TH2, inhibiting the increasing of IgE
9. Inhibiting degranulation of mast cells
10. Promoting production of epidermal growth factor (EGF) and angiogenic factor(AF)
11. Promoting production of natural moisturizing factor (NMF)
12. Blocking allergens
13. Skin permeability
14. Large molecule produce a soft, breathable and moisturizing film on the skin

Features

1. Best water-solubility
2. Best permeability
3. Best skin-friendly
4. Best stability
5. Best cooperativity
6. Non medical modification
7. Safe and efficient

Dosage

1-20% (based on 1% β-glucan concentration)

Package

20kg/bucket

Storage

Stored in cool and dry place protected from light, keep drum close when not in use.

Shelf Life

24 months under prescribed storage conditions and airtight packing. 

Storage

Under room temperature away from light

This product is developed by our R&D company Ulcho Biochemical Ltd (http://www.ulcho.com/).

This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).