Structure of Ezetimibe CAS 163222-33-1

Ezetimibe CAS 163222-33-1

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

163222-33-1

Name

Ezetimibe

Synonyms

(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone [ACD/IUPAC Name]
(3R,4S)-1-(4-Fluorophényl)-3-[(3S)-3-(4-fluorophényl)-3-hydroxypropyl]-4-(4-hydroxyphényl)-2-azétidinone [French] [ACD/IUPAC Name]
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one
(3R,4S)-1-(4-fluorophényl)-3-[(3S)-3-(4-fluorophényl)-3-hydroxypropyl]-4-(4-hydroxyphényl)azétidin-2-one
(3R,4S)-1-(4-Fluorphenyl)-3-[(3S)-3-(4-fluorphenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinon [German] [ACD/IUPAC Name]
(3R,4S)-1-(4-Fluorphenyl)-3-[(3S)-3-(4-fluorphenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-on
2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)- [ACD/Index Name]
ezetimiba [Spanish] [INN]
ezetimibe [BAN] [INN] [JAN] [USAN] [Wiki]
ézétimibe [French] [INN]
ezetimibum [Latin] [INN]
Ezetrol [Trade name]
Zetia [Trade name]
эзетимиб [Russian] [INN]
إيزيتيميب [Arabic] [INN]
依泽麦布 [Chinese] [INN]
(-)-Sch 58235
(3R,4S)-1-(4-fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one
(3R,4S)-1-(4-Fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone, sch-58235
(3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxy-propyl]-4-(4-hydroxyphenyl)azetidin-2-one
(3R,4S)-1,4-fluorophenyl-3-[(3S-3-4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-2-azetidinone
[163222-33-1]
1-(4-flurophenyl)-(3R)-3-(4-flurophenyl)-(3S)-hydroxypropyl-(4S)-(4-hydroxyphenyl)-2-azetidinone
163222-33-1 [RN]
2-Azetidinone, 1-(4-fluorophenyl)-3-((3S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-, (3R,4S)-
2-Azetidinone, 1-(4-fluorophenyl)-3-(3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)-, (3R-(3α(S*),4β))-
7981967 [Beilstein]
Ezedoc
Ezedoc (Trade name)
Ezedoc; Ezetib; Zient
Ezetib
Ezetib (Trade name)
MFCD00937872 [MDL number]
MLS000759443
QA-3288
SCH 58235|SCH-58235|Zetia®
SMR000466334
UNII-EOR26LQQ24
Zetia (TN)
Zetia®
Zient

Molecular Structure

Structure of Ezetimibe CAS 163222-33-1

Structure of Ezetimibe CAS 163222-33-1

SMILES

c1cc(ccc1[C@@H]2[C@H](C(=O)N2c3ccc(cc3)F)CC[C@@H](c4ccc(cc4)F)O)O

StdInChI

InChI=1S/C24H21F2NO3/c25-17-5-1-15(2-6-17)22(29)14-13-21-23(16-3-11-20(28)12-4-16)27(24(21)30)19-9-7-18(26)8-10-19/h1-12,21-23,28-29H,13-14H2/t21-,22+,23-/m1/s1

StdInChIKey

OLNTVTPDXPETLC-XPWALMASSA-N

Molecular Formula

C24H21F2NO3

Molecular Weight

409.43

Properties

Appearance

White crystalline powder

Melting Point

164-166℃

Specifications and Other Information of Our Ezetimibe CAS 163222-33-1

Standard

Enterprise standard

Identification Methods

HNMR/HPLC

Purity

98%min

Storage

Under the room temperature and away from light

Application

Ezetimibe is a new class of selective inhibitors of cholesterol absorption by the small intestine brush border membrane vesicle membrane protein (relative molecular mass 145X103) binding, inhibition of intestinal diet and transported to the bile in the gut the absorption of cholesterol, reduce serum and liver cholesterol levels, for the treatment of cardiovascular disease.

Links

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details.
http://www.caming.com/ezetimibe-cas-163222-33-1/

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/ezetimibe-cas-163222-33-1/