DMPU CAS 7226-23-5
Identification
Name
DMPU
CAS Number
7226-23-5
Synonyms
1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
1,3-Dimethyl-2-oxohexahydropyrimidine
N,N′-Dimethylpropylene urea
N,N’-Dimethyl-N,N’-trimethyleneurea
1,3-Dimethyltetrahydro-2(1H)-pyrimidinon
1,3-Dimethyltetrahydro-2(1H)-pyrimidinone
1,3-Diméthyltétrahydro-2(1H)-pyrimidinone
1,3-Dimethyltetrahydropyrimidin-2(1H)-one
2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-
Tetrahydro-1,3-dimethyl-2(1H)-pyrimidinone
1,3-dimethyl-1,3-diazaperhydroin-2-one
1,3-dimethyl-1,3-diazinan-2-one
1,3-Dimethyl-2-oxohexahydropyrimidine
1,3-DIMETHYL-3,4,5,6- TETRAHYDRO-2-PYRIMIDINONE
1,3-Dimethyl-3,4,5,6-tetrahydro-2 -pyrimidinone
1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
1,3-Dimethyl-tetrahydro-pyrimidin-2-one
2-PYRIMIDONE,TETRAHYDRO,1,3-DIMETHYL
N,N’-Dimethyltrimethyleneurea
N,N’-ジメチルプロピレン尿素
tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one
Tetrahydro-1,3-dimethyl-2(1H)pyrimidine
Molecular Structure
Structure Analysis
a. The strong electrophilic effect of carbonyl structure makes DMPU an aprotic polar solvent with high boiling point, high flash point and low melting point which is easy to use in filtration, distillation, solvent extraction and so on;
b. Very low toxicity, negligible harm to human body and less pollution to the environment;Its high solubility can dissolve organic, inorganic, resins, polymers, etc.. It also has activation properties with various reagents and miscibility with other high-boiling solvents;
c. The excellent stability makes it stable even under hot strong alkaline or acidic condition as well as resistance against water, light and oxygen.
SMILES
CN1CCCN(C1=O)C
StdInChI
InChI=1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3
StdInChIKey
GUVUOGQBMYCBQP-UHFFFAOYSA-N
Molecular Formula
C6H12N2O
Molecular Weight
128.17
EINECS Number
230-625-6
Beilstein Registry Number
110562
MDL Number
MFCD00006550
Properties
Appearance
Colourless transparent liquid
Boiling Point
246 ºC
Melting Point
-20 ºC
Flash Point
121 ºC
Density
1.064 g/mL at 25 °C(lit.)
Refractive Index
n20/D 1.4875-1.4895(lit.)
Viscosity
1.944cp/25℃
Safety Data
Symbol
GHS05,GHS07,GHS08
Signal Word
Danger
Hazard Statements
Precautionary Statements
Personal Protective Equipment
Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
23-26-36/37/39
WGK Germany
2
RTECS
UW7582500
Specifications and Other Information of Our DMPU CAS 7226-23-5
Purity
99.5% min(By GC)
Identification Method
HNMR, GC
Water
0.1% max
PH
6.5-8.0
Colour
20 max
Impurity
0.2% max
Known Application
DMPU is used as a solvent to promote the dissolution of reactants, accelerate the reaction rate, improve the reaction yield and replace toxic solvents, which can be applied to pharmaceutical excipients. Together with drugs and other excipients, DMPU can promote drugs’ dissolution and mixing, enhance the stability and transdermal absorption capacity and prolong the action.
DMPU in the application of pharmaceutical preparations: the body of the epidermis is a physiological barrier, it prevents the entry of in vitro substances, so the need for external preparations to promote the absorption of the skin to promote the solvent. This solvent should meet the following requirements: active drug groups can quickly and reliably reach the site of injury: do not stimulate the skin, non-toxic; long time to save stability. DMPU can dissolve a variety of drugs, the human body is almost no toxicity, with the above requirements, so it can be used as a drug accessories. DMPU and other excipients and pharmaceutical ingredients can promote the dissolution and mixing of drugs to enhance the stability of the drug and transdermal absorption capacity, to extend the role of time.
Productivity
600MT/year
Storage
Room temperature away from light
