structure of DMPU CAS 7226-23-5

DMPU CAS 7226-23-5

Identification

Name

DMPU

CAS Number

7226-23-5

Synonyms

1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
1,3-Dimethyl-2-oxohexahydropyrimidine
N,N′-Dimethylpropylene urea
N,N’-Dimethyl-N,N’-trimethyleneurea
1,3-Dimethyltetrahydro-2(1H)-pyrimidinon
1,3-Dimethyltetrahydro-2(1H)-pyrimidinone
1,3-Diméthyltétrahydro-2(1H)-pyrimidinone
1,3-Dimethyltetrahydropyrimidin-2(1H)-one
2(1H)-Pyrimidinone, tetrahydro-1,3-dimethyl-
Tetrahydro-1,3-dimethyl-2(1H)-pyrimidinone
1,3-dimethyl-1,3-diazaperhydroin-2-one
1,3-dimethyl-1,3-diazinan-2-one
1,3-Dimethyl-2-oxohexahydropyrimidine
1,3-DIMETHYL-3,4,5,6- TETRAHYDRO-2-PYRIMIDINONE
1,3-Dimethyl-3,4,5,6-tetrahydro-2 -pyrimidinone
1,3-dimethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
1,3-Dimethyl-tetrahydro-pyrimidin-2-one
2-PYRIMIDONE,TETRAHYDRO,1,3-DIMETHYL
N,N’-Dimethyltrimethyleneurea
N,N’-ジメチルプロピレン尿素
tetrahydro-1,3-dimethyl-1H-pyrimidin-2-one
Tetrahydro-1,3-dimethyl-2(1H)pyrimidine

Molecular Structure

structure of DMPU CAS 7226-23-5

Structure Analysis

a. The strong electrophilic effect of carbonyl structure makes DMPU an aprotic polar solvent with high boiling point, high flash point and low melting point which is easy to use in filtration, distillation, solvent extraction and so on;
b. Very low toxicity, negligible harm to human body and less pollution to the environment;Its high solubility can dissolve organic, inorganic, resins, polymers, etc.. It also has activation properties with various reagents and miscibility with other high-boiling solvents;
c. The excellent stability makes it stable even under hot strong alkaline or acidic condition as well as resistance against water, light and oxygen.

SMILES

CN1CCCN(C1=O)C

StdInChI

InChI=1S/C6H12N2O/c1-7-4-3-5-8(2)6(7)9/h3-5H2,1-2H3

StdInChIKey

GUVUOGQBMYCBQP-UHFFFAOYSA-N

Molecular Formula

C6H12N2O

Molecular Weight

128.17

EINECS Number

230-625-6

Beilstein Registry Number

110562

MDL Number

MFCD00006550

Properties

Appearance

Colourless transparent liquid

Boiling Point

246 ºC

Melting Point

-20 ºC

Flash Point

121 ºC

Density

1.064 g/mL at 25 °C(lit.)

Refractive Index

n20/D 1.4875-1.4895(lit.)

Viscosity

1.944cp/25℃

Safety Data

Symbol

corrosion-jpg exclamation-mark-jpghealth-hazard-jpgGHS05,GHS07,GHS08

Signal Word

Danger

Hazard Statements

H302-H318-H361f

Precautionary Statements

P280-P305+P351+P338

Personal Protective Equipment

Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

Hazard Codes (Europe)

Xn

Risk Statements (Europe)

22-36-43

Safety Statements (Europe)

23-26-36/37/39

WGK Germany

2

RTECS

UW7582500

Specifications and Other Information of Our DMPU CAS 7226-23-5

Purity

99.5% min(By GC)

Identification Method

HNMR, GC

Water

0.1% max

PH

6.5-8.0

Colour

20 max

Impurity

0.2% max

Known Application

DMPU is used as a solvent to promote the dissolution of reactants, accelerate the reaction rate, improve the reaction yield and replace toxic solvents, which can be applied to pharmaceutical excipients. Together with drugs and other excipients, DMPU can promote drugs’ dissolution and mixing, enhance the stability and transdermal absorption capacity and prolong the action.
DMPU in the application of pharmaceutical preparations: the body of the epidermis is a physiological barrier, it prevents the entry of in vitro substances, so the need for external preparations to promote the absorption of the skin to promote the solvent. This solvent should meet the following requirements: active drug groups can quickly and reliably reach the site of injury: do not stimulate the skin, non-toxic; long time to save stability. DMPU can dissolve a variety of drugs, the human body is almost no toxicity, with the above requirements, so it can be used as a drug accessories. DMPU and other excipients and pharmaceutical ingredients can promote the dissolution and mixing of drugs to enhance the stability of the drug and transdermal absorption capacity, to extend the role of time.

Productivity

600MT/year

Storage

Room temperature away from light

Watson-Int Link

http://watson-int.com/DMPU_CAS_7226-23-5.html