Diflucortolone valerate CAS 59198-70-8

Identification

CAS Number

59198-70-8

Name

Diflucortolone valerate

Synonyms

(6α,11β,16α)-6,9-Difluor-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-ylvalerat [German] [ACD/IUPAC Name]
(6α,11β,16α)-6,9-Difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl valerate [ACD/IUPAC Name]
1A63Z067C8
59198-70-8 [RN]
6-a,9-Difluoro-11-b-hydroxy-16-a-methyl-21-valeryloxy-1,4-pregnadiene-3,20-dione
Afusona [Trade name]
Diflucortolone 21-valerate
Diflucortolone valerate [JAN] [Wiki]
Neriforte [Trade name]
Nerisona [Trade name]
Nerisone [Trade name]
Pentanoic acid, (6α,11β,16α)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl ester [ACD/Index Name]
Temetex [Trade name]
Texmeten [Trade name]
UNII-1A63Z067C8
Valérate de (6α,11β,16α)-6,9-difluoro-11-hydroxy-16-méthyl-3,20-dioxoprégna-1,4-dién-21-yle [French] [ACD/IUPAC Name]
(6α,11β,16α)-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl pentanoate
[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] pentanoate
[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] pentanoate
[59198-70-8]
2-((6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl pentanoate
35367-38-5 [RN]
6α,9-Difluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-valerate
6-α,9-Difluoro-11-β-hydroxy-16-α-methyl-21-valeryloxy-1,4-pregnadiene-3,20-dione
6-α,9-Difluoro-11-β-hydroxy-21-valeryloxy-16-α-methyl-1,4-pregnadiene-3,20-dione
DFV
Diflucortolonvalerianat [German]
Diflucortolonvalerianat [German]
Difluocortolone valerianate
EINECS 261-655-8
MFCD00468095 [MDL number]
Nerisone Forte
pentanoic acid [2-[(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] ester
Pregna-1,4-diene-3,20-dione, 6,9-difluoro-11-hydroxy-16-methyl-21-((1-oxopentyl)oxy)-, (6-α,11-β,16-α)-
Travazol
UNII:1A63Z067C8
valeric acid [2-[(6S,8S,9R,10S,11S,13S,14S,16R,17S)-6,9-difluoro-11-hydroxy-3-keto-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
ジフルコルトロン [Japanese]

Molecular Structure

SMILES

CCCCC(=O)OCC(=O)[[email protected]]1[[email protected]@H](C[[email protected]@H]2[[email protected]@]1(C[[email protected]@H]([[email protected]]3([[email protected]]2C[[email protected]@H](C4=CC(=O)C=C[[email protected]@]43C)F)F)O)C)C

StdInChI

InChI=1S/C27H36F2O5/c1-5-6-7-23(33)34-14-21(31)24-15(2)10-17-18-12-20(28)19-11-16(30)8-9-26(19,4)27(18,29)22(32)13-25(17,24)3/h8-9,11,15,17-18,20,22,24,32H,5-7,10,12-14H2,1-4H3/t15-,17+,18+,20+,22+,24-,25+,26+,27+/m1/s1

StdInChIKey

HHJIUUAMYGBVSDYTFFSALGSA-N

Molecular Formula

C27H36F2O5

Molecular Weight

478.569 

MDL Number

MFCD00468095

Properties

Appearance

White or almost white,crystalline powder

Safety Data

WGK Germany

3

Specifications and Other Information of Our Diflucortolone valerate CAS 59198-70-8

Identification Methods

HPLC

Content

97.0%~102.0%

Specific Optical Rotation

+98.0°~ +103.0°

Particle Size

99% ≤ 30u

Loss on Drying

≤0.5%

Residue on Ignition

≤0.2%

Residual Solvents

THF:≤720ppm

Methanol: ≤3000ppm

Dichloromethane: ≤600ppm

Pyridine: ≤200ppm

Chloroform: ≤60ppm

Related Substances

Total impurities: ≤2.0%

The biggest impurity: ≤1.0%

Shelf Life

3 years

Storage

Under room temperature away from light

Known Application

Used as the Pharmaceutical intermediate.

This product is developed by our sub R&D company Caming Pharmaceutical Ltd, and please click the link below for details. http://www.caming.com/diflucortolone-valerate-cas-59198-70-8/ This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details. http://www.watson-int.com/diflucortolone-valerate-cas-59198-70-8/
Posted in Caming Pharmaceutical Ltd, Products, Steroid Hormones