[Bis(trifluoroacetoxy)iodo]benzene CAS 2712-78-9
Identification
CAS Number
2712-78-9
Name
[Bis(trifluoroacetoxy)iodo]benzene
Synonyms
[Bis(trifluoroacetoxy)iodo]benzene
Iodine, phenylbis[(2,2,2-trifluoroacetyl)oxy]-
Phenyl[bis(2,2,2-trifluoroacetoxy)]-λ3-iodane
phenyl{bis[(trifluoroacetyl)oxy]}-λ3-iodane
(Bis(trifluoroacetoxy)iodo)benzene
3,5-Bis(trifluoromethyl)benzonitrile
Bis(I,I-trifluoroacetoxy)iodobenzene
Bis(trifluoroacetoxy)iodobenzene
BTI
BTI; Iodobenzene I,I-bis(trifluoroacetate); PIFA
Iodine, phenylbis(trifluoroacetato-O)-
Iodobenzene I,I-bis(trifluoroacetate)
iodophenyl(2,2,2-trifluoroacetyloxy)methyl 2,2,2-trifluoroacetate
Iodosobenzene bis(trifluoroacetate)
Phenylbis(trifluoroacetato-O)iodine
PIFA
Molecular Structure
SMILES
FC(F)(F)C(=O)OI(OC(=O)C(F)(F)F)c1ccccc1
StdInChI
InChI=1S/C10H5F6IO4/c11-9(12,13)7(18)20-17(6-4-2-1-3-5-6)21-8(19)10(14,15)16/h1-5H
StdInChIKey
PEZNEXFPRSOYPL-UHFFFAOYSA-N
MDL Number
MFCD00009672
Beilstein Registry Number
764767
EINECS
220-308-0
Molecular Formula
C10H5F6IO4
Molecular Weight
430.04
Properties
Appearance
Off-white crystal
Melting Point
121-126 °C
Safety Data
Symbol
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
26-36
WGK Germany
3
Specifications and Other Information of Our [Bis(trifluoroacetoxy)iodo]benzene CAS 2712-78-9
Identification Methods
HNMR, HPLC
Assay
98% min
Loss on Drying
0.5% max
Productivity
300kg/month
Application
Reactant or reagent for:
• Pummerer-like reactions
• Chemoselective deprotection of dimethoxybenzyl ethers
• Mediating oxidative cycloisomerization
• Tosyloxylation of anilides
Used for the direct α-hydroxylation of ketones under acidic conditions. Also employed as a p-fluorination reagent of 4-alkylphenols in the presence of HF·pyridine for synthesis of 4-fluorocyclohexa-2,5-dienones.
Reagent for the oxidation of N-acylhydrazones to 1,3,4-oxadiazoles. Promotes the cyclization of styryl amines to N-alkyl or N-aryl indoles.
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