Azathramycin CAS 76801-85-9

Identification

CAS Number

76801-85-9

Name

Azathramycin

Synonyms

Azaerythromycin A
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2, 6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside [ACD/IUPAC Name]
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranoside
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-Ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-15-oxo-11-{[3,4,6-tridesoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadecan-13-yl-2 ,6-didesoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosid [German] [ACD/IUPAC Name]
1-Oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β -D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)- [ACD/Index Name]
1-oxa-6-azacyclopentadecan-15-one, 13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-
2,6-Didésoxy-3-C-méthyl-3-O-méthyl-α-L-ribo-hexopyranoside de (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-éthyl-3,4,10-trihydroxy-3,5,8,10,12,14-hexaméthyl-15-oxo-11-{[3,4,6-tridésoxy-3-(diméthylamino) -β-D-xylo-hexopyranosyl]oxy}-1-oxa-6-azacyclopentadécan-13-yle [French] [ACD/IUPAC Name]
4LSP9FJT5B
76801-85-9 [RN]
9-Deoxo-9a-aza-9a-homoerythromycin A
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-3,4,10-trihydroxy-13-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyl-tetrahydropyran-2-yl]oxy-3,5,8,10,12,14-hexamethyl-1-oxa-6-azacyclopentadecan-15-one
[76801-85-9] [RN]
6-Demethylazithromycin
6-Demethylazithromycin (Azaerythromycin A)
9-DEOXO-9 α-AZA-9 α-HOMO ERYTHROMYCIN A
Azaerythromycin A;9-Deoxo-9a-aza-9a-homoerythromycin A;Desmethyl Azithromycin
Azathramycin
Azithromycin [USP] [Wiki]
azithromycin a
desmethyl
DESMETHYL AZITHROMYCIN
MFCD09038719 [MDL number]
UNII:4LSP9FJT5B
UNII-4LSP9FJT5B

SMILES

CC[[email protected]@H]1[[email protected]@]([[email protected]@H]([[email protected]](NC[[email protected]@H](C[[email protected]@]([[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](C(=O)O1)C)O[[email protected]]2C[[email protected]@]([[email protected]]([[email protected]@H](O2)C)O)(C)OC)C)O[[email protected]]3[[email protected]@H]([[email protected]](C[[email protected]](O3)C)N(C)C)O)(C)O)C)C)O)(C)O

StdInChI

InChI=1S/C37H70N2O12/c1-14-26-37(10,45)30(41)23(6)38-18-19(2)16-35(8,44)32(51-34-28(40)25(39(11)12)15-20(3)47-34)21(4)29(22(5)33(43)49-26)50-27-17-36(9,46-13)31(42)24(7)48-27/h19-32,34,38,40-42,44-45H,14-18H2,1-13H3/t19-,20-,21+,22-,23-,24+,25+,26-,27+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1

StdInChIKey

HRKNNHYKWGYTEN-HOQMJRDDSA-N

Molecular Formula

C₃₇H₇₀N₂O₁₂

Molecular Weight

734.958

MDL Number

MFCD09038719

Properties

Appearance

White to almost white powder

Safety Data

Signal Word

Danger

WGK Germany

3

Specifications and Other Information of Our Azathramycin CAS 76801-85-9

Identification Methods

HNMR, HPLC

Purity

≥90%

Specific Optical Rotation

-40°~-47°

Residue on Ignition

≤1%

Water

≤5%

Related Substances

AZA-I (RRT 0.57)

≤1%

AZA-L (RRT 0.72)

≤1%

AZA-F (RRT 0.92)

≤2%

AZA-B (RRT 1.4)

≤1%

AZA-Q (RRT 1.08)

≤1.5%

AZA-E (RRT 2.5)

≤1%

Any other single impurity

≤1%

Shelf Life

2 years

Storage

Store in room temperature for long time, in container tightly sealed; Protect from light.

Known Application

Used as a intermediates.

Links

This product is developed by our R&D company Caming Pharmaceutical Ltd (https://www.caming.com/).

This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).