319460-85-0 Axitinib - Watsonnoke Scientific Ltd

Identification
Properties
Safety Data
Specifications & Other Information
Links

Identification

CAS Number

319460-85-0

Name

Axitinib

Key intermediates of the Axitinib

CAS:886230-77-9;Name:(E)-6-iodo-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:885126-35-2;Name:N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-yl]thio]benzamide
CAS:86230-76-8
CAS:20054-45-9;Name:N-methyl-2-sulfanylbenzamide

Synonyms

319460-85-0 [RN]
8720
axitinib [Spanish] [INN]
axitinib [French] [INN]
Axitinib [INN] [USAN] [Wiki]
axitinibum [Latin] [INN]
Benzamide, N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-
Benzamide, N-methyl-2-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]- [ACD/Index Name]
C9LVQ0YUXG
N-Methyl-2-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamid [German] [ACD/IUPAC Name]
N-Methyl-2-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide [ACD/IUPAC Name]
N-Méthyl-2-({3-[(E)-2-(2-pyridinyl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide [French] [ACD/IUPAC Name]
N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide
N-Methyl-2-({3-[(E)-2-(pyridin-2-yl)vinyl]-1H-indazol-6-yl}sulfanyl)benzamide
N-methyl-2-[[3-[2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
UNII-C9LVQ0YUXG
акситиниб [Russian] [INN]
أكسيتينيب [Arabic] [INN]
阿昔替尼 [Chinese] [INN]
(E)-N-methyl-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
(E)-N-methyl-2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)benzamide
(trans-4-Methylpyrrolidin-3-yl)methanol
[319460-85-0]
{2-[3-((1E)-2-(2-pyridyl)vinyl)(1H-indazol-6-ylthio)]phenyl}-N-methylcarboxamide
319463-51-9 [RN]
70356-09-1 [RN]
945723-36-4 [RN]
AG 013736|AG-013736|AG013736|Inlyta®
AG013736
AG-013736; AG 013736; AG013736
AG13736
Avobenzone [INN] [USAN] [USP] [Wiki]
AXI
Axitinib (AG 013736)
Axitinib [USAN]
axitinibum
Axtintib
Benzamide, N-methyl-2-((3-((1E)-2-(2-pyridinyl)ethenyl)-1H-indazo)-6-yl)thio)-
Inlyta
Inlyta®
MFCD09837898 [MDL number]
MFCD14708210
N-Methyl-[[3[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide
N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-i ndazol-6-yl)sulfanyl)benzamide
N-Methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide
N-methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]-benzamide
N-Methyl-2-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
N-methyl-2-[[3-[(E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
N-methyl-2-[[3-[(E)-2-(2-pyridyl)vinyl]-1H-indazol-6-yl]sulfanyl]benzamide
N-methyl-2-[[3-[(E)-2-(2-pyridyl)vinyl]-1H-indazol-6-yl]thio]benzamide
N-Methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide
N-methyl-2-[[3-[(Z)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]thio]benzamide
N-Methyl-2-[3-(2-pyridin-2-yl-vinyl)-1H-indazol-6-ylsulfanyl]-benzamide
N-methyl-2-3-(1E)-2-(2-pyridinyl)ethenyl-1H-indazol-6-ylthio-benzamide
S1005
UNII:C9LVQ0YUXG

Molecular Structure

Structure of Axitinib CAS 319460-85-0

SMILES

CNC(=O)c1ccccc1Sc2ccc3c(c2)[nH]nc3/C=C/c4ccccn4

StdInChI

InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+

StdInChIKey

RITAVMQDGBJQJZ-FMIVXFBMSA-N

Molecular Formula

C22H18N4OS

Molecular Weight

386.47

MDL Number

MFCD09837898

Appearance

Pale yellow powder or off-white powder

Safety Data

Symbol

HS07, GHS09

Signal Word

Warning

Hazard Statements

H302-H400

Precautionary Statements

P273

RIDADR

UN 3077 9 / PGIII

WGK Germany

Specifications and Other Information of Our Axitinib CAS 319460-85-0

Standard

Enterprise standard

Identification Methods

HNMR,HPLC

Purity

99%min

Loss on Drying

≤1.0%

Residue on Ignition

≤ 1.0%

Single max Impurity

≤ 0.3%

Total Impurities