Atipamezole CAS 104054-27-5
Identification
Name
Atipamezole
CAS Number
104054-27-5
Synonyms
1H-imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
1H-imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
Atipamezole
4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
4-(2-Ethyl-2-indanyl)imidazole
4-(2-Ethyl-indan-2-yl)-1H-imidazole(Atipamezole)
4-(2-ethylindan-2-yl)imidazole
Antisedan
Antisedan
Atipamezol
Atipamezolum
Molecular Structure
SMILES
n1cc(nc1)C3(Cc2c(cccc2)C3)CC
StdInChI
InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)
StdInChIKey
HSWPZIDYAHLZDD-UHFFFAOYSA-N
Molecular Formula
C14H16N2
Molecular Weight
212.29
MDL Number
MFCD00864502
Properties
Appearance
White Solid
Solubility
DMSO≥30 mg/mL
Boiling Point
367.131 °C at 760 mmHg
Flash Point
178.006 °C
Density
1.116g/mL
Safety Data
Symbol
GHS06Signal Word
Danger
Hazard Statements
Precautionary Statements
Personal Protective Equipment
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Hazard Codes (Europe)
Risk Statements (Europe)
Safety Statements (Europe)
45
RIDADR
UN 2811 6.1/PG 3
WGK Germany
3
Specifications and Other Information of Our Atipamezole CAS 104054-27-5 (Hydrochloride CAS 104075-48-1)
Purity
98%min(By HPLC)
Identification Method
NMR, HPLC
Biochem/physiol Actions
Atipamezole is more potent than yohimbine; it is very selective for alpha2-adrenergic vs alpha1sites, but not selelctive for alpha2 – subtypes.
Known Application
Atipamezole is a synthetic alpha2-adrenergic antagonist, indicated for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been researched in humans as a potential anti-Parkinsonian drug.
Productivity
1Kg/month
Storage
Sealed, away from light, 2-8°C for long time storage
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