Structure of Atipamezole CAS 104054-27-5

Atipamezole CAS 104054-27-5

Identification

Name

Atipamezole

CAS Number

104054-27-5

Synonyms

1H-imidazole, 4-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
1H-imidazole, 5-(2-ethyl-2,3-dihydro-1H-inden-2-yl)-
5-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
Atipamezole
4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole
4-(2-Ethyl-2-indanyl)imidazole
4-(2-Ethyl-indan-2-yl)-1H-imidazole(Atipamezole)
4-(2-ethylindan-2-yl)imidazole
Antisedan
Antisedan
Atipamezol
Atipamezolum

Molecular Structure

Structure of Atipamezole CAS 104054-27-5

Structure of Atipamezole CAS 104054-27-5

SMILES

n1cc(nc1)C3(Cc2c(cccc2)C3)CC

StdInChI

InChI=1S/C14H16N2/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14/h3-6,9-10H,2,7-8H2,1H3,(H,15,16)

StdInChIKey

HSWPZIDYAHLZDD-UHFFFAOYSA-N

Molecular Formula

C14H16N2

Molecular Weight

212.29

MDL Number

MFCD00864502

Properties

Appearance

White Solid

Solubility

DMSO≥30 mg/mL

Boiling Point

367.131 °C at 760 mmHg

Flash Point

178.006 °C

Density

1.116g/mL

Safety Data

Symbol

skull-jpgGHS06

Signal Word

Danger

Hazard Statements

H301

Precautionary Statements

P301+P310

Personal Protective Equipment

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Hazard Codes (Europe)

T

Risk Statements (Europe)

25

Safety Statements (Europe)

45

RIDADR

UN 2811 6.1/PG 3

WGK Germany

3

Specifications and Other Information of Our Atipamezole CAS 104054-27-5 (Hydrochloride CAS 104075-48-1)

Purity

98%min(By HPLC)

Identification Method

NMR, HPLC

Biochem/physiol Actions

Atipamezole is more potent than yohimbine; it is very selective for alpha2-adrenergic vs alpha1sites, but not selelctive for alpha2 – subtypes.

Known Application

Atipamezole is a synthetic alpha2-adrenergic antagonist, indicated for the reversal of the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been researched in humans as a potential anti-Parkinsonian drug.

Productivity

1Kg/month

Storage

Sealed, away from light, 2-8°C for long time storage

General View of Documents

Atipamezole CAS 104054-27-5 HPLC

Atipamezole CAS 104054-27-5 HPLC

Watson-Int Link

http://www.watson-int.com/Atipamezole_CAS_104054-27-5.html