2′,3′,5′-Tri-O-acetyluridine CAS 4105-38-8

Identification

CAS Number

4105-38-8

Name

2′,3′,5′-Tri-O-acetyluridine

Synonyms

2′,3′,5′-Triacetyluridine
223-881-5
[EINECS]
2WP61F175M
[UNII]
2′,3′,5-TRI-ACETYLURIDINE
2′,3′,5′-Tri-O-acetyluridin
[German]
[IUPAC name – generated by ACD/Name]
2′,3′,5′-Tri-O-acetyluridine
[IUPAC name – generated by ACD/Name]
2′,3′,5′-Tri-O-acétyluridine
[French]
[IUPAC name – generated by ACD/Name]
2′,3′,5′-triacetate uridine
2′,3′,5′-Triacetyluridine
4105-38-8
[RN]
triacétate d’uridine
[French]
[INN]
triacetato de uridina
[Spanish]
[INN]
Uridine 2′,3′,5′-triacetate
uridine triacetate
[INN]
[USAN]
Uridine, 2′,3′,5′-triacetate
[Index name – generated by ACD/Name]
uridini triacetas
[Latin]
[INN]
Vistogard
[Trade name]
Xuriden
[Trade name]

SMILES

CC(=O)OC[C@H]1OC@@HC@H[C@@H]1OC(C)=O

StdInChI

InChI=1S/C15H18N2O9/c1-7(18)23-6-10-12(24-8(2)19)13(25-9(3)20)14(26-10)17-5-4-11(21)16-15(17)22/h4-5,10,12-14H,6H2,1-3H3,(H,16,21,22)/t10-,12-,13-,14-/m1/s1

StdInChIKey

AUFUWRKPQLGTGF-FMKGYKFTSA-N

Molecular Formula

C15H18N2O9

Molecular Weight

370.319

EINECS

223-881-5

MDL Number

MFCD07798677

Properties

Appearance

White or almost white crystalline powder

Safety Data

RIDADR 

NONH for all modes of transport

Specifications and Other Information of Our 2′,3′,5′-Tri-O-acetyluridine CAS 4105-38-8

Identification Methods

HNMR, HPLC

Purity

≥98%

Heavy Metals(As Pb)

≤0.002%

Loss on Drying

≤1.0%

Residue on Ignition

≤0.20%

Shelf Life

3 years

Storage

Store at room temperature, Sealed and away from light.

Known Application

1. Treatment of Hereditary Orotic Aciduria This product is an orphan drug indicated for the treatment of the rare genetic disorder, hereditary orotic aciduria. It functions by replenishing endogenous uridine levels, correcting metabolic disturbances, and ameliorating associated hematopoietic and growth abnormalities in patients. 2. Chemotherapy Antidote Specifically indicated for the management of toxicity resulting from overdoses of the chemotherapeutic agents 5-fluorouracil and capecitabine. It serves to alleviate severe adverse effects induced by chemotherapy, including cardiac, neurological, and gastrointestinal toxicities, as well as neutropenia.

This product is developed by our R&D company Caming Pharmaceutical Ltd (https://www.caming.com/).

This product is developed by our R&D company Watson International Ltd (https://www.watson-int.com/).