Structure of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol CAS 121660-11-5

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol CAS 121660-11-5

Identification

CAS Number

121660-11-5

Name

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol

Synonyms

(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol
[2-Cyclopropyl-4-(4-fluorophényl)-3-quinoléinyl]méthanol [French] [ACD/IUPAC Name]
[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methanol [ACD/IUPAC Name]
[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol
[2-Cyclopropyl-4-(4-fluorphenyl)-3-chinolinyl]methanol [German] [ACD/IUPAC Name]
121660-11-5 [RN]
3-Quinolinemethanol, 2-cyclopropyl-4-(4-fluorophenyl)- [ACD/Index Name]
(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)met
[121660-11-5] [RN]
[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]methan-1-ol
1346600-49-4 [RN]
2-cyclopropan-4-(4-fluorophenyl)-3-quinoline methanol
2-Cyclopropyl-4-(4-Fluorophenyl) -3-quinolinemethanol
2-Cyclopropyl-4-(4-fluorophenyl) -quinolyl-3-methanol
2-Cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol
2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol-d5
2-Cyclopropyl-4-(4-Fluorophenyl)quinoline-3-Methanol (en)
2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol
2-环丙基-4-(4-氟苯基)-3-喹啉甲醇 [Chinese]
DS-12057
Ethyl 5-amino-1H-pyrrolo[2,3-c]pyridine-2-carboxylate [ACD/IUPAC Name]
MFCD09032924 [MDL number]
Less…

SMILES

Fc4ccc(c1c3ccccc3nc(c1CO)C2CC2)cc4

StdInChI

InChI=1S/C19H16FNO/c20-14-9-7-12(8-10-14)18-15-3-1-2-4-17(15)21-19(13-5-6-13)16(18)11-22/h1-4,7-10,13,22H,5-6,11H2

StdInChIKey

FIZDBNPUFMDGFZ-UHFFFAOYSA-N

Molecular Formula

C19H16FNO

Molecular Weight

293.335

MDL Number

MFCD09032924

Properties

Appearance

White to light yellow powder or crystal

Safety Data

Symbol

exclamation-mark-jpgGHS07

Signal Word

Warning

Hazard statements

H302, H315, H319, H335

Precautionary Statements

P261, P305, P338, P351

WGK Germany

3

Specifications and Other Information of Our

Purity

99% min

Melting point

132~137°C

Impurity I(Destluoro)

≤4.1%

Individual impurity

≤0.1%

Total impurities

≤1.0%

Loss on drying

≤0.5%

Shelf Life

2 years

Known Application

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol is an intermediate in the synthesis of Pitavastatin calcium, a statin medication primarily used to lower cholesterol and prevent cardiovascular diseases. As an intermediate, it plays several crucial roles in the drug synthesis process: As an intermediate, 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol helps to enhance the synthesis efficiency of Pitavastatin calcium, making the production process more efficient and controllable.

The quality and purity of the intermediate directly affect the final drug’s quality. High-quality intermediates contribute to producing Pitavastatin calcium with higher purity and fewer side effects.

Choosing the appropriate intermediate in the drug synthesis process can minimize unnecessary by-products, thereby reducing the final drug’s side effects.

The structure of 2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol contributes to the pharmacological activity of Pitavastatin calcium, making it more effective in lowering cholesterol and preventing cardiovascular diseases.

General View of Documents

This product is developed by our R&D company Caming Pharmaceutical Limited (http://www.caming.com/).

This product is sold exclusively through our sales company Watson International Limited, and please click the link below for details (https://www.watson-int.com/).