Structure of 1-Ferrocenylethanol CAS 1277-49-2

1-Ferrocenylethanol CAS 1277-49-2

Identification

CAS Number

1277-49-2

Name

1-Ferrocenylethanol

Synonyms

α-Ferrocenylethanol
α-Methylferrocenemethanol
(1-Hydroxyethyl)ferrocene
NSC 162110

Molecular Structure

Structure of 1-Ferrocenylethanol CAS 1277-49-2

SMILES

CC(C1=CC=CC1[Fe]C2C=CC=C2)O

StdInChI

InChI=1S/C7H9O.C5H5.Fe/c1-6(8)7-4-2-3-5-7;1-2-4-5-3-1;/h2-6,8H,1H3;1-5H;

SydInChIKey

NJPGTUIMEAOISI-UHFFFAOYSA-N

Molecular Formula

C12H14FeO

Molecular Weight

230.08

MDL Number

MFCD00013752

Properties

Appearance

Yellow or off-yellow powder

Melting Point

76-79 °C(lit.)

Safety Data

Symbol

exclamation-mark-jpgGHS07

Signal Word

Warning

Hazard Statements

H315-H319-H335

Precautionary Statements

P261-P305 + P351 + P338

Personal Protective Equipment

dust mask type(N95) US, Eye Shields, Gloves

Hazard Codes (Europe)

Xi

Risk Statements (Europe)

36/37/38

Safety Statements (Europe)

26-36

WGK Germany

3

RTECS

LK0730000

MSDS Download

MSDS of 1-Ferrocenylethanol CAS 1277-49-2

Specifications and Other Information of Our 1-Ferrocenylethanol CAS 1277-49-2

Purity

98%min(By HPLC)

Identification Method

HNMR, HPLC

Known Actions

  • Ligand in titanium-catalyzed intermolecular hydroamination of terminal alkynes (Markovnikov vs. anti-Markovnikov addition)

Reactant for

  • Single-electron transfer living radical polymerization reactions
  • Preparation of ferrocene-modified thiopyrimidines as anticancer agents
  • Preparation of rersible addition-fragmentation chain transfer (RAFT) agent for RAFT polymerization of styrene

Known Application

Ferrocenyl derivative exhibits physiological activity of anti-malarial, anti-tumor, bactericidal, anti-inflammatory, treatment of anemia, inhibition of enzymatic activity and so on by virtue of its unique structure and diverse properties,

  • Good stability, low toxicity;
  • Aromatic, easy for substitution reaction and modification; Hydrophobic, attacking a variety of enzymes in cells, DNA, RNA by going through cell membrane;
  • Strong selectivity by its thickness of the sandwich structure, which can stop it close to the activity site of enzymes; Redox reversibility, which enable it to involve in metabolism by enzymes. So nowadays, ferrocenyl derivative has wide applications to biological and medical fields such as ferrocene-modified beta-lactam.

Productivity

500kg/month

General View of Documents

1-Ferrocenylethanol CAS 1277-49-2 HNMR and HPLC

1-Ferrocenylethanol CAS 1277-49-2 HNMR and HPLC

Watson-Int Link

http://watson-int.com/1-(Ferrocenyl)ethanol_CAS_1277-49-2.html

0 replies

Leave a Reply

Want to join the discussion?
Feel free to contribute!

Leave a Reply

Your email address will not be published.